Results 111 to 120 of about 8,292 (268)

N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line

Nature Communications
IgG secreted by B cells carry asparagine N(297)-linked glycans in the fragment crystallizable (Fc) region. Changes in Fc glycosylation are related to health or disease and are functionally relevant, as IgG without Fc glycans cannot bind to Fcɣ receptors ...
Theresa Kissel, Veerle F. A. M. Derksen, Arthur E. H. Bentlage, Carolien Koeleman, Lise Hafkenscheid, Diane van der Woude, Manfred Wuhrer, Gestur Vidarsson, René E. M. Toes   +8 more
doaj   +1 more source

Plant expression systems for production of hemagglutinin as a vaccine against influenza virus. [PDF]

, 2014
Many examples of a successful application of plant-based expression systems for production of biologically active recombinant proteins exist in the literature.
Góra-Sochacka, Anna, Kamel, Katarzyna Anna, Redkiewicz, Patrycja, Sirko, Agnieszka   +3 more
core  

Bay‐functionalized [7]Helicene Bilayer Nanographenes

Advanced Optical Materials, EarlyView.
Bay‐functionalized [7]helical bilayer nanographenes are synthesized via a scalable, modular strategy enabling late‐stage diversification. Tailored methoxy, diketone, and phenazine substitutions precisely tune redox, photophysical, and chiroptical properties, delivering strong electronic circular dichroism and bright circularly polarized luminescence ...
Anmol Thanai, Vikas Sharma, Louis Minion, Hassan Khan, Hadeel Abbas, George F. S. Whitehead, Avantika Hasija, Jessica Wade, Matthew John Fuchter, Ashok Keerthi   +9 more
wiley   +1 more source

Ultra‐Flexible Dual‐Band Organic Photodetectors for Visible and Near‐Infrared Sensing

Advanced Optical Materials, EarlyView.
An ultra‐flexible dual‐band organic photodetector with a total thickness of 5.6 µm for bio‐sensing is developed. It selectively detects visible and near‐infrared light with high sensitivity by switching the voltage. Peripheral oxygen saturation (SpO2) measurement is demonstrated using the device attached to a finger under a single light source by ...
Sachi Awakura, Hiroaki Jinno, Yusaku Tagawa, Ryota Fukuzawa, Masahito Takakuwa, Takao Someya, Tomoyuki Yokota   +6 more
wiley   +1 more source

Structural aspects of molecular recognition in the immune system. Part I: Acquired immunity (IUPAC Technical Report) [PDF]

, 2017
Humoral immunity allows the body to mount a defense against pathogens and foreign substances, and to respond with memory to subsequent exposures. The molecular participants may also recognize self-structures, leading to attack on the body and autoimmune ...
Moehle, Kerstin, Templeton, Douglas M.
core  

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

Advanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu, Bin Cui, Xumin Huang, Xiaoyu (Rayne) Zheng, T. Thang Vo‐Doan, Ruirui Qiao   +5 more
wiley   +1 more source

Preparation of Anti-idiotype Antibody as Diagnostic Kit in Rabies Serological Test [PDF]

, 2014
Serology remains the only way to monitor the effectiveness of vaccination of humans and animals against rabies. Many techniques for determining the level of rabies antibodies have been described, and all of the methods used rabies viruses as antigen ...
NAWANGSIH, E. N. (EKA), PARYATI, S. P. (SAYU), RAKHMAT, I. I. (IIS)   +2 more
core  

Mastering Complexity toward High‐Performance Multi‐Principal Element Alloy‐Based Films and Coatings: A Review on Microstructural Regulation and Property Optimization

Advanced Science, EarlyView.
This review provides a comprehensive exploration of microstructure regulation strategies for multi‐principal element alloy‐based films and coatings, with a focus on the interplay between elemental composition, nanoscale architecture, heterostructures and interfacial engineering in tailoring their properties and functions. A systematic analysis of their
Jiaming Cao, Jiayi Sun, Heqing Li, Zhiqiang Wu, Xianghai An   +4 more
wiley   +1 more source

PM10 Impairs CD56dim NK Cell Cytotoxicity via FNBP1 Suppression to Exacerbate Rheumatoid Arthritis: Insights from Multimodal Multi‐Omics

Advanced Science, EarlyView.
This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao, Qinyang Zhang, Yu Jiang, Dagang Tang, Xiao Qu, Jun Zhang, Yi Chen, Weixia Duan, Tao Li, Zhengwei Cai, Yanran Huang, Xiaoji Luo   +11 more
wiley   +1 more source

Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations

Advanced Science, EarlyView.
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl, Nandan Haloi, Marta Carroni, Shengpan Zhang, Quentin James Sattentau, Erdinc Sezgin, Lucie Delemotte, Rebecca J. Howard   +7 more
wiley   +1 more source