Results 171 to 180 of about 122,949 (273)

Editorial: Safety consideration in the development of anti-tumor monoclonal antibodies during drug development. [PDF]

Front Oncol
Wang T, Abedin SE, van der Laan JW.
europepmc   +1 more source

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Bispecific antibodies in the treatment of epithelial ovarian, endometrial, and cervical cancer: an overview of current applications, challenges, and emerging opportunities. [PDF]

Explor Target Antitumor Ther
Parola S, Colombo I.
europepmc   +1 more source

Improved performance of a rapid immunochromatographic assay for detection of PBP2a in non-Staphylococcus aureus staphylococcal species [PDF]

, 2019
Arnold, Amanda R, Burd, Eileen M, Burnham, Carey-Ann D, Canver, Matthew C, Ford, Bradley A, Gonzalez, Mark D, Jenkins, Stephen G, Lawhon, Sara D, Westblade, Lars F   +8 more
core   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Kinetically Controlling Surface Atom Arrangements in Thermally Robust, Amorphous High‐Entropy Alloy Nanoparticles by Solvent Selection

Advanced Science, EarlyView.
This work leverages the level of carbon supersaturation in the metallic constituents during particle formation to regulate nanoparticle morphology, structure, and composition distribution. The solvent‐dependent (C/(C+O)) ratio and the relative kinetics of the competing reactions of carbon shell formation, coalescence of metallic constituents, and ...
Varatharaja Nallathambi, Se‐Ho Kim, Andrea M. Mingers, Petra Ebbinghaus, Baptiste Gault, Sven Reichenberger, Dierk Raabe, Stephan Barcikowski   +7 more
wiley   +1 more source

Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]

Foods
Zhou T, Zhang H, Yu X, Pan K, Yao X, Shen X, Lei H.   +6 more
europepmc   +1 more source

Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation

Advanced Science, EarlyView.
From conventional ceramics to bioinspired smart composites, this review charts the evolution of dental restorative biomaterials. Integrating materials innovation, advanced manufacturing technologies, and bioinspired strategies, it presents a roadmap for developing functional, clinically translatable restorations that combine durability, adaptability ...
Bailei Li, Ruixue Ai, Xinjiani Chen, Yaning Wang, Chenlei Pan, Suxian Song, Chenjie Yang, Yu Zhou, Zhen Zhang, Xiaojun Liu, Xiaodi Liu, Liping Yao, Quanbao Zhang, Wenxue Gu, Rongqing Zhang   +14 more
wiley   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Construction of an Immunosensor Based on the Affinity DNA Functional Ligands to the Fc Segment of IgG Antibody. [PDF]

Biosensors (Basel)
Yang Q, Liu Z, Xu X, Zhao Z, Fan Z, Du B, Xu J, Xu J, Wang J, Liu B, Mu X, Tong Z.   +11 more
europepmc   +1 more source