The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement-dependent cytotoxicity. [PDF]
Pinto AJ +9 more
europepmc +1 more source
Cycling water‐in‐salt batteries involves complex degradation processes that require multiprobe analysis. Using online electrochemical mass spectrometry (OEMS), postmortem X‐ray photoemission spectroscopy (XPS) (including hard‐XPS), and scanning electron microscopy (SEM), the degradation mechanisms are examined in composite electrodes (TiS2 and LiFePO4)
Célia Doublet +7 more
wiley +1 more source
Abstract Recruiting and retaining school leaders is a challenge in many systems worldwide. Previous research has identified three distinct ways in which succession planning can be conceptualised and approached: a ‘pipeline’ approach seeks to match supply and demand for the posts that need filling; a ‘pool’ strategy involves proactively identifying and ...
Toby Greany +3 more
wiley +1 more source
Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]
Zhou T +6 more
europepmc +1 more source
Between public service and market: Portraying the bifront university in a platformized world
Abstract This paper contributes to the international debate on the changes affecting recruitment and orientation processes toward higher education. Based on qualitative research involving 19 Italian public universities, the study analyses the transformations in communication, recruitment and orientation activities within platformization and increasing ...
Marco Pitzalis +2 more
wiley +1 more source
Middle-Down Nuclear Magnetic Resonance for Therapeutic Monoclonal Antibody Glycan Profiling. [PDF]
Li J, Zhang G, Chen K.
europepmc +1 more source
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier +3 more
wiley +1 more source
Bispecific antibodies in the treatment of epithelial ovarian, endometrial, and cervical cancer: an overview of current applications, challenges, and emerging opportunities. [PDF]
Parola S, Colombo I.
europepmc +1 more source
Targeting a Dynamic Protein-Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex [PDF]
Cota, E +4 more
core +1 more source

