Single-domain antibodies for brain targeting [PDF]
Lalatsa, Katerina, Moreira Leite, Diana
core +1 more source
Citropin 1.3 is an antimicrobial peptide derived from amphibians that forms amyloid structures. Here, the structural and functional properties of citropin 1.3 are characterized. Using high‐resolution imaging approaches, a variety of canonical and undescribed fibril morphologies are identified.
Fabio Strati +8 more
wiley +1 more source
Editorial: Safety consideration in the development of anti-tumor monoclonal antibodies during drug development. [PDF]
Wang T, Abedin SE, van der Laan JW.
europepmc +1 more source
Calcium‐Ion Insertion Chemistry in Tunneled α‐MnO2 Cathodes for Calcium Metal Batteries
α‐MnO2 cathodes demonstrate distinct electrochemical behavior and Ca2+ storage capabilities depending on whether they are paired with activated carbon anodes or Ca metal anodes. Ca2+ insertion/extraction is only feasible when α‐MnO2 cathodes are cycled against Ca metal anodes.
Shuangshuang Cui +7 more
wiley +1 more source
Switchbody, an Antigen‐Responsive Enzyme Switch Based on Antibody and Its Working Principle
This paper presents an antibody‐based enzyme switch, termed a “Switchbody”, which is fused with an enzyme‐derived fragment to the N‐terminus of an antibody. As its working principle, the fused fragment is trapped within the antibody and released upon antigen binding, leading to enzyme reconstitution and a subsequent increase in enzyme activity.
Takanobu Yasuda +10 more
wiley +1 more source
Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]
Zhou T +6 more
europepmc +1 more source
Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay +3 more
wiley +1 more source
Diffusion, search and attack motions of antibodies. [PDF]
Biehl R +5 more
europepmc +1 more source
Improved performance of a rapid immunochromatographic assay for detection of PBP2a in non-Staphylococcus aureus staphylococcal species [PDF]
Arnold, Amanda R +8 more
core +1 more source
Synthesis of Functional Materials Using N‐heterocyclic Amines Beyond Melamine
Melamine has long enabled supramolecular assemblies, polymers, and carbon nitrides, yet related N‐heterocyclic amines remain underexplored. This review highlights advances with melamine analogues such as 6‐phenyl‐, 6‐methyl‐triazine diamines and 2,4,6‐triaminopyrimidine, focusing on how structural variation governs reactivity, condensation, and ...
Jesús Barrio, Arne Thomas
wiley +1 more source

