Production of site-specific antibody conjugates using metabolic glycoengineering and novel Fc glycovariants. [PDF]
Bernstein ZJ+9 more
europepmc +1 more source
Monoclonal antibody biosimilars for cancer treatment. [PDF]
Broer LN+6 more
europepmc +1 more source
T-Cell Engager Therapy in Prostate Cancer: Molecular Insights into a New Frontier in Immunotherapy. [PDF]
Kwon WA, Joung JY.
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CuH‐catalyzed olefin hydrogenation is rare compared to those of carbonyl‐derived substrates. Olefin insertion into Cu‐H to form Cu‐alkyl is ubiquitous; however, subsequent H2 activation remains unknown to our knowledge. Herein, we investigated the transformations of β‐H elimination, H2 cleavage, and catalytic olefin hydrogenation in a series of linear ...
Evan Patrick+6 more
wiley +1 more source
Structural insights into epitope-paratope interactions of a monoclonal antibody targeting CEACAM5-expressing tumors. [PDF]
Kumar A+5 more
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Controlling the Crystallization Kinetics of Low Loss Phase Change Material Sb2S3
This paper explores the glass dynamics and crystallization kinetics of antimony sulfide (Sb2S3), and its implications for optoelectronic technologies. It highlights how adjusting sample dimensions influences crystallization kinetics, shifting from growth‐driven to nucleation‐driven processes. The findings emphasize the importance of understanding these
Felix Hoff+4 more
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Analytical Characterization for Similarity Assessment Between an Aflibercept Biosimilar SB15 and Reference Product (Eylea®). [PDF]
Lee H+7 more
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Solid State Self‐Assembly of an Extended Curved‐Arm Nickel(II) Macrocycle with Fullerene C60
Three co‐crystalline structures that contain fullerene C60 and (5,14‐dihydro‐6,8,15,17‐tetrabenzyl‐2,3,11,12‐tetramethyldibenzo[b,i][1,4,8,11]tetraazacyclotetradecine)nickel(II) show the formation discrete one‐dimensional hollow channels as a results of 1 : 1 interplay and 1 : 2 dimeric interplay with the fullerenes arranged in hexagonal arrays ...
Irene Ling+4 more
wiley +1 more source
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley +1 more source
Physiologically based pharmacokinetic models for systemic disposition of protein therapeutics in rabbits. [PDF]
Jairam RK, Franz M, Hanke N, Kuepfer L.
europepmc +1 more source