Results 191 to 200 of about 122,949 (273)

Application of Synchrotron Radiation Based X‐Ray Diffraction in Zeolite Research: Advanced Analysis from Atomic Structure to Dynamic Behavior

Advanced Science, EarlyView.
Synchrotron Radiation‐based X‐ray Diffraction (SR‐XRD) offers high‐resolution insights and real‐time monitoring of zeolite synthesis, structural transformations, and catalytic reactions, advancing zeolite‐based catalyst development. However, challenges such as data interpretation and technological limitations remain.
Weihua Wang, Chenxin Gong, Mingming Chen, Nan Zhang, Jingqing Zhang, Jing Shi, Hongxing Liu, Jiawei Teng, Jianqiang Wang, Yongfeng Hu   +9 more
wiley   +1 more source

Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology. [PDF]

Proc Natl Acad Sci U S A
Bayer AC, Sanmarco LM, Pellerin A, Masi G, Plasencia A, Anderson JM, Nowak RJ, Damato V, Massacesi L, Pham MC, Khani-Habibabadi F, Vital H, Higginson-Scott N, Otipoby KL, Xing Y, Mascanfroni ID, O'Connor KC.   +16 more
europepmc   +1 more source

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

Advanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li, Zezhong Yu, Tao Pu, Yanling Wu, Gang Wang, Youhua Xie, Tianlei Ying, Zhenlin Yang, Yibing Shi   +8 more
wiley   +1 more source

Comparative Structure Activity Relationship Characterization of the Biosimilar BAT1806/BIIB800 to Reference Tocilizumab. [PDF]

BioDrugs
Liu Y, Xie J, Li Z, Mei X, Cao D, Li S, Engle L, Liu S, Ebbers HC, Liu C.   +9 more
europepmc   +1 more source

Shape‐Determined Kinetic Pathways in 2D Solid–Solid Phase Transitions

Advanced Science, EarlyView.
By simulating 2D ball‐stick pentagon, hexagon, and octagon systems, the kinetics of solid–solid phase transition is investigated, which is characterized by the loss of body‐orientation order. During which, the local defects of body‐orientation self‐organize into three different patterns, originated from the shape‐determined kinetic pathways, which may ...
Ruijian Zhu, Yi Peng, Yanting Wang
wiley   +1 more source

Monoclonal Antibodies: Historical Perspective and Current Trends in Biological Drug Development. [PDF]

Int J Mol Sci
Madej B, Tomaszewski F, Szmajda-Krygier D, Świechowski R, Jeleń A, Mirowski M.   +5 more
europepmc   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

A Narrative Review of Pemphigoid Diseases: Bridging Associations, Comorbidities, and Management. [PDF]

Dermatol Ther (Heidelb)
Myers EL, Culton DA.
europepmc   +1 more source

Dissolution Study of Biodegradable Magnesium Silicide Thin Films for Transient Electronic Applications

Advanced Science, EarlyView.
Magnesium silicide (Mg2Si) is introduced as a narrow‐bandgap, biodegradable semiconductor for transient electronics. RF‐sputtered and annealed Mg2Si thin films show high intrinsic electrical conductivity and low thermal conductivity. The polycrystalline material undergoes hydrolysis in aquatic and composting environments with minimal cytotoxicity ...
Ji‐Woo Gu, Jun‐Seok Shim, Minjung Chae, Yoonseong Jung, Su‐Min Kim, Young‐In Ryu, Jae‐Hwan Lee, Sung‐Woo Kim, Kyung‐Sub Kim, Tae‐Woo Lee, Edyta Wyszkowska, Jungho Shin, Hyejin Jang, Ju‐Young Kim, Myoung‐Ryul Ok, Jong‐hyoung Kim, Jae‐Young Bae, Seung‐Kyun Kang   +17 more
wiley   +1 more source

Rheumatoid factor and anti-citrullinated protein IgA antibodies in the diagnosis, prognosis and monitoring of patients with rheumatoid arthritis. [PDF]

J Transl Autoimmun
Steffen U, Sieghart D, Steiner G.
europepmc   +1 more source