Results 191 to 200 of about 197,879 (225)

Activation and Fixation of Atmospheric CO2 through a 1,2,3‐Triazole‐Based Mesoionic Carbene–Borane Adduct

Chemistry – A European Journal, EarlyView.
A triazole‐based mesoionic carbene (MIC)–borane compound captures atmospheric CO2 and converts it into formate. The rate and product formation of CO2 reduction is seen to be strongly dependent on the CO2 source with both formate and bicarbonate being produced with the same MIC–borane compound.
Maren Neubrand, Jessica Stubbe, Richard Rudolf, Robert R. M. Walter, Maite Nößler, Biprajit Sarkar   +5 more
wiley   +1 more source

Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study. [PDF]

Nat Commun
Koester A, Witcher DR, Lee M, Demarest SJ, Potter S, Werle K, Bauer S, Ruiz D, Malherbe L, Poorbaugh J, Glasebrook A, Preuss C, Datta G, Wang Z, Knorr J, Manner D, Patel D, Schmitz C, Klekotka P, Nirula A.   +19 more
europepmc   +1 more source

Structural Insights Into Amyloid Polymorphism: The Impact of Glutamine to Norleucine Substitutions in GNNQQNY Aggregation

Chemistry – A European Journal, EarlyView.
In the wild‐type GNNQQNY, self‐assembly is extremely fast and many intermediate structures are masked. By studying the selectively disrupted hydrogen‐bonding variants, the data show that GNNQNleNY stabilizes at the protofibril stage, GNNQQNY progresses to achiral nanocrystals and GNNNleQNY evolves to twisted chiral fibers.
Fruzsina Bencs, Loránd Románszki, Viktor Farkas, András Perczel   +3 more
wiley   +1 more source

IGLV3-21^R110-directed bispecific antibodies activate T cells and promote killing in a high-risk subset of chronic lymphocytic leukemia

Fischer C, Stücheli S, Chen S, Nimmerfroh J, Schultheiß C, Widmer C, Heim D, Kasenda B, Passweg J, Kobold S, Egli L, Coianiz N, Chijioke O, Chiorazzi N, Follo M, Läubli H, Peipp M, Binder M.   +17 more
europepmc   +1 more source

Biomimetic Growth of Calcium Oxalate Hydrates: Shape Development and Structures in Agar Gel Matrices

Chemistry – A European Journal, EarlyView.
The biomimetic growth of calcium oxalate hydrates is conducted using a double diffusion technique in agar gel. The results reveal the shape development of calcium oxalate monohydrate (COM) and dihydrate (COD), resembling biominerals of kidney stones. The pH variations influence phase selection, with COM forming at lower pH and COD at higher pH.
Annu Thomas, Paul Simon, Wilder Carrillo‐Cabrera, Elena Sturm   +3 more
wiley   +1 more source

An Oxoiron(IV) Complex Supported by an N‐Alkylated Cyclam Ligand System Containing a Pendant Alcohol Moiety

Chemistry – A European Journal, EarlyView.
Depending on the pendant atom present in the N‐alkylated cyclam (1,4,8,11‐tetraazacyclotetradecane) based ligand framework, substantially altered conformations of the non‐heme iron(IV)‐oxo intermediates are revealed. Abstract The effect of a pendant neutral alcohol moiety in the N‐alkylated cyclam (1,4,8,11‐tetraazacyclotetradecane) ligand backbone is ...
Dibya Jyoti Barman, Thomas Lohmiller, Sagie Katz, Michael Haumann, Peter Hildebrandt, Wonwoo Nam, Kallol Ray   +6 more
wiley   +1 more source

The Role of STEAP1 in Prostate Cancer: Implications for Diagnosis and Therapeutic Strategies. [PDF]

Biomedicines
Zhang L, Ren X, An R, Song H, Tian Y, Wei X, Shi M, Wang Z.   +7 more
europepmc   +1 more source

From Donor‐Acceptor Ligands to Smart Coordination Polymers: Cyanothiazole‐Cu(I) Complexes for Multifunctional Electronic Devices

Chemistry – A European Journal, EarlyView.
Cyanothiazoles, paired with copper(I) iodide, form complexes with luminescent properties. X‐ray crystallography revealed two types of coordination polymers, while spectroscopic, synchrotron, and electric measurements supported by density functional (DFT) calculations studies highlighted their unique electronic features, offering a foundation for future
Karolina Gutmańska, Agnieszka Podborska, Tomasz Mazur, Andrzej Sławek, Ramesh Sivasamy, Alexey Maximenko, Łukasz Orzeł, Janusz Oszajca, Grażyna Stochel, Amarjith V. Dev, Chakkooth Vijayakumar, Konrad Szaciłowski, Anna Dołęga   +12 more
wiley   +1 more source

Asymmetric Total Synthesis of (+)‐ and (−)‐Myrioneurinol Employing a “Resolutive” Late‐Stage Barton‐McCombie Deoxygenation

Chemistry – A European Journal, EarlyView.
The total syntheses of (+)‐ and (−)‐myrioneurinol are described. This was achieved through two key steps based on a Prins‐type alkenylation of activated phenols to construct the central cycle of this natural substance, and a late‐stage “resolutive” Barton Mc‐Combie reaction which allowed the separation as well as the deoxygenation of both enantiomers ...
Adrien Denizet, Rajesh Nomula, Richard Edwards, Patrick Y. Toullec, Philippe A. Peixoto   +4 more
wiley   +1 more source