Results 61 to 70 of about 197,780 (132)

Fluctuations and Symmetry Energy in Nuclear Fragmentation Dynamics [PDF]

, 2012
Within a dynamical description of nuclear fragmentation, based on the liquid-gas phase transition scenario, we explore the relation between neutron-proton density fluctuations and nuclear symmetry energy. We show that, along the fragmentation path, isovector fluctuations follow the evolution of the local density and approach an equilibrium value ...
arxiv   +1 more source

Non-targeted characterization of attributes affecting antibody-FcγRIIIa V158 (CD16a) binding via online affinity chromatography-mass spectrometry

mAbs, 2022
Antibodies facilitate targeted cell killing by engaging with immune cells such as natural killer cells through weak binding interactions with Fcγ receptors on the cell surface.
Daniel W. Woodall, Thomas M. Dillon, Kevin Kalenian, Rupa Padaki, Scott Kuhns, David J. Semin, Pavel V. Bondarenko   +6 more
doaj   +1 more source

The Dynamical Fate of Self-Gravitating Disc Fragments After Tidal Downsizing [PDF]

, 2014
The gravitational instability model of planet/brown dwarf formation proposes that protostellar discs can fragment into objects with masses above a few Jupiter masses at large semimajor axis. Tidal downsizing may reduce both the object mass and semimajor axis.
arxiv   +1 more source

Cahn and Sivers effects in the target fragmentation region of SIDIS [PDF]

arXiv, 2005
LEPTO event generator is modified to describe the azimuthal modulations arising from Cahn and Sivers effects. The comparisons with some existing data in the current fragmentation region of SIDIS are presented. The predictions for Cahn and Sivers asymmetries in the target fragmentation region are presented for SIDIS of 12 GeV electrons off proton target.
arxiv  

Identification of a novel mechanism of action of bovine IgG antibodies specific for Staphylococcus aureus

Veterinary Research, 2018
Staphylococcus aureus is a major pathogen that causes subclinical mastitis associated with huge economic losses to the dairy industry. A few vaccines for bovine mastitis are available, and they are expected to induce the production of S.
Mutsumi Furukawa, Hiroshi Yoneyama, Eiji Hata, Hidetomo Iwano, Hidetoshi Higuchi, Tasuke Ando, Mika Sato, Tomohito Hayashi, Yoshio Kiku, Yuya Nagasawa, Kanae Niimi, Katsuki Usami, Kumiko Ito, Kouichi Watanabe, Tomonori Nochi, Hisashi Aso   +15 more
doaj   +1 more source

MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation

Frontiers in Immunology, 2020
Current approaches to study glycosylation of polyclonal human immunoglobulins G (IgG) usually imply protein digestion or glycan release. While these approaches allow in-depth characterization, they also result in a loss of valuable information regarding ...
Thomas Sénard, Andrea F. G. Gargano, Andrea F. G. Gargano, David Falck, Steven W. de Taeye, Steven W. de Taeye, Theo Rispens, Gestur Vidarsson, Manfred Wuhrer, Govert W. Somsen, Elena Domínguez-Vega   +10 more
doaj   +1 more source

Destruction of massive fragments in protostellar disks and crystalline silicate production [PDF]

, 2011
We present a mechanism for the crystalline silicate production associated with the formation and subsequent destruction of massive fragments in young protostellar disks. The fragments form in the embedded phase of star formation via disk fragmentation at radial distances \ga 50-100 AU and anneal small amorphous grains in their interior when the gas ...
arxiv   +1 more source

PCSK9 stimulates Syk, PKCδ, and NF-κB, leading to atherosclerosis progression independently of LDL receptor

Nature Communications
Proprotein convertase subtilisin/kexin type-9 (PCSK9) binds to and degrades low-density lipoprotein (LDL) receptor, leading to increase of LDL cholesterol in blood. Its blockers have emerged as promising therapeutics for cardiovascular diseases.
Dasom Shin, Soungchan Kim, Hwan Lee, Hyun-Chae Lee, Jaewon Lee, Hyun-woo Park, Mina Fukai, EunByule Choi, Subin Choi, Bon-Jun Koo, Ji-Hoon Yu, Gyurae No, Sungyoon Cho, Chan Woo Kim, Dohyun Han, Hyun-Duk Jang, Hyo-Soo Kim   +16 more
doaj   +1 more source

Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy

Molecular Therapy: Oncology
Neospora caninum, a potential anticancer agent able to reactivate the immune response within the tumor microenvironment (TME), has recently shown enhanced immunomodulatory properties in different tumor models when armed with the cytokine, Il-15.
Clément Riviere, Muna Aljieli, Marie-Noëlle Mévélec, Louis Lantier, Fanny Boursin, Laurie Lajoie, Céline Ducournau, Stéphanie Germon, Nathalie Moiré, Isabelle Dimier-Poisson, Nicolas Aubrey, Anne di Tommaso   +11 more
doaj  

The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains

Frontiers in Immunology, 2017
N-linked glycosylation of the fragment crystallizable (Fc)-region of immunoglobulin G (IgG) is known to have a large influence on the activity of the antibody, an effect reported to be IgG subclass specific. This situation applies both to humans and mice.
Noortje de Haan, Karli R. Reiding, Jasminka Krištić, Agnes L. Hipgrave Ederveen, Gordan Lauc, Manfred Wuhrer   +5 more
doaj   +1 more source