Results 61 to 70 of about 222 (121)

Cell-free DNA fragmentomics for preeclampsia risk assessment

Nature Communications
Abstract Preeclampsia (PE) is a pregnancy-specific hypertensive disorder that could lead to serious maternal and fetal complications, yet early identification of women at risk remains challenging because reliable biomarkers are limited.
Wenqiu Xu, Songchang Chen, Jia Li, Si Zhou, Yanning Yin, Zhixu Qiu, Jianguo Zhang, Cong Liu, Qiang Zhao, Gefei Xiao, Yan Zhou, Zhiguang Zhao, Xiao Zhang, Wenzhi Yang, Yunfang Wang, Huiqin Li, Zhen Yang, Suihua Feng, Qun Zhang, Weiping Chen, Huahua Li, Xiaohong Ruan, Hua Li, Sufen Zhang, Liqing Hu, Jie Qin, Wuyan Huang, Zhongzhe Li, Xianling Cao, Xuanyou Zhou, Naixin Xu, Dongxia Hou, Hong Dong, Jie Wang, Yaxian Liu, Quanfu Zhang, Xiaohua Wang, Lijian Zhao, Hefeng Huang, Chenming Xu   +39 more
openaire   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Abstracts

Cancer Science, Volume 116, Issue S1, Page 1-1975, January 2025.
wiley   +1 more source

Protein-oligopeptide fragmentomics

, 2008
8
openaire   +2 more sources

Seminal plasma cfDNA fragmentomics landscape delineates male infertility subtypes

Clinical Epigenetics
Abstract Background While cell-free DNA (cfDNA) fragmentomics has transformed liquid biopsy applications in prenatal screening and oncology, its potential in male reproductive health remains uncharted. Methods Through integrated whole-genome sequencing and jagged end sequencing (Jag-Seq) coupled with non-CpG methylation analysis, we ...
Wu, Xiaoyu, Meng, Fan, Zhang, Huiping, Li, Zeqing, Zhao, Kai   +4 more
openaire   +2 more sources

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science
ABSTRACT Cell‐free DNA (cfDNA) in plasma consists of short DNA fragments resulting from a non‐random fragmentation process, with distinct fragmentomic characteristics that are related with their cellular origins. Here, we report that somatic variant signatures in cfDNA markedly differ between non‐cancerous controls and cancer patients,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
openaire   +2 more sources

Exploring global cfDNA fragmentomics as a biomarker in real-world patients with melanoma

Journal of Investigative Dermatology
Circulating cell-free DNA fragmentomics-the analysis of cell-free DNA fragment-length profiles-has been explored as a biomarker across cancers, but evidence in melanoma is limited. We conducted a longitudinal prospective study of 235 patients with American Joint Committee on Cancer stages II-IV melanoma (549 plasma samples) and 11 phenotypic high-risk ...
Daniel Rizo-Potau, Anton Forniés-Mariné, José Luis Villanueva-Cañas, Michelle Aguilar, Cristina Sánchez-Cárdenas, Teresa Torres, Sebastian Podlipnik, Cristina Carrera, Susana Puig, Josep Malvehy, Joan Anton Puig-Butillé   +10 more
openaire   +2 more sources

DeepFRAG: a method for cancer detection based on DNA fragmentomics and deep learning

Bioinformatics Advances
Abstract Motivation Cancer screening using liquid biopsy technology has become standard in modern clinical and preventive oncology. This method analyzes cell-free DNA (cfDNA) circulating in a patient’s bloodstream.
Andrey Koch, Eldar Giladi
openaire   +3 more sources

Commentary: Techniques for removal of posteriorly dislocated lens fragment. [PDF]

Indian J Ophthalmol, 2023
Babu N, Kohli P.
europepmc   +1 more source

Editorial: The emerging role of liquid biopsy in gastrointestinal, pancreatic and liver cancers. [PDF]

Front Med (Lausanne), 2023
Iacob R, Paul D, Popescu I.
europepmc   +1 more source