Results 71 to 80 of about 261 (136)

Mechanistic Modeling of cfDNA Fragmentome Dynamics Predicts Progression to Immunotherapy

BackgroundPlasma cell-free DNA (cfDNA) shows promise as predictive cancer biomarker, but mechanisms governing cfDNA production/fragmentation/elimination dynamics, and their relationships with tumor burden and disease progression, remain poorly understood.
Boutonnet, Audrey, Salas, Sebastien, Nguyen Phuong, Linh, Tomasini, Pascale, Greillier, Laurent, Garcia, Jean-Charles, Ginot, Frédéric, Deville, Jean-Laurent, Fina, Frédéric, Benzekry, Sébastien   +9 more
core   +1 more source

-fragmentome)

, 2015

core   +2 more sources

Protein-oligopeptide fragmentomics

, 2008
8
openaire   +2 more sources

Computational modeling approaches for circulating cellfree DNA in oncology

International audienceMany cancer patients undergoing immune-checkpoint inhibition (ICI) experience early progression (EP), defined as progression at the first imaging evaluation.
Nguyen Phuong, Linh
core   +1 more source

Systematic biases in reference-based plasma cell-free DNA fragmentomic profiling

Cell Reports Methods
Plasma cell-free DNA (cfDNA) fragmentation patterns are emerging directions in cancer liquid biopsy with high translational significance. Conventionally, the cfDNA sequencing reads are aligned to a reference genome to extract their fragmentomic features.
Xiaoyi Liu, Mengqi Yang, Dingxue Hu, Yunyun An, Wanqiu Wang, Huizhen Lin, Yuqi Pan, Jia Ju, Kun Sun   +8 more
openaire   +3 more sources

Circulating cell-free DNA size distribution as a prediction marker for early progression undergoing immune checkpoint inhibitors

International audienceIntroduction: Despite a significant proportion (20 to 40%)[1] of advanced cancer patients having long-term response to treatment with immune checkpoint inhibitors (ICI), many of them do not respond at all and experience early ...
Boutonnet, Audrey, Fina, Frederic, Nguyen Phuong, Linh, Greillier, Laurent, Gaudy-Marqueste, Caroline, Salas, Sébastien, Ginot, Frédéric, Deville, Jean-Laurent, Benzekry, Sébastien   +8 more
core   +1 more source

Commentary: Techniques for removal of posteriorly dislocated lens fragment. [PDF]

Indian J Ophthalmol, 2023
Babu N, Kohli P.
europepmc   +1 more source

Holistic Integration of Deep Learning Models for Mass Spectrometry-Based Peptide Identification

Tandem mass spectrometry (MS/MS) coupled with liquid chromatography and/or ion mobility separation is an essential experimental technique for high-throughput discovery of the proteome, or the collection of proteins in a biological system.
Yang, Kevin
core   +1 more source

Sinteza nove piridinijeve soli s triazolilidenskim fragmentom

, 2020
This thesis describes the synthesis of a novel pyridinium salt bearing triazolylidene fragment bounded to pyridine nitrogen atom, which has not yet been described in the literature. The synthesized salt represents a potential bidentate dicarbene NHC ligand, useful for the formation of transition metal NHC complexes.
openaire   +1 more source

Peptide MS/MS-fragmentome

, 2015

core   +1 more source