Results 31 to 40 of about 57,728 (258)

Practical Considerations in the Management of Frail Older People with Diabetes

Diseases
With increasing life expectancy, the number of older people living with comorbid diabetes and frailty is increasing. The development of frailty accelerates diabetes-related adverse outcomes.
Dima Abdelhafiz, Ahmed Abdelhafiz
doaj   +1 more source

Description of frail older people profiles according to four screening tools applied in primary care settings: a cross sectional analysis

BMC Geriatrics, 2019
Background Regarding the health care of older populations, WHO recommends shifting from disease-driven attention models towards a personalized, integrated and continuous care aimed to the maintenance and enhancement of functional capacities.
Itziar Vergara, Maider Mateo-Abad, María Carmen Saucedo-Figueredo, Mónica Machón, Alonso Montiel-Luque, Kalliopi Vrotsou, María Antonia Nava del Val, Ana Díez-Ruiz, Carolina Güell, Ander Matheu, Antonio Bueno, Jazmina Núñez, Francisco Rivas-Ruiz   +12 more
doaj   +1 more source

Validation of the clinical frailty score (CFS) in French language

BMC Geriatrics, 2019
Background Very old critical ill patients are a rapid expanding group. To better understand the magnitude of the challenges involved in intensive care practice for an ageing population and discuss a rational allocation of resources, healthcare ...
Paul Abraham, Delphine S. Courvoisier, Cedric Annweiler, Cliff Lenoir, Thomas Millien, Francoise Dalmaz, Hans Flaatten, Rui Moreno, Steffen Christensen, Dylan W. de Lange, Bertrand Guidet, Karim Bendjelid, Bernhard Walder, Bernardo Bollen Pinto   +13 more
doaj   +1 more source

Patients' inability to perform a preoperative cardiopulmonary exercise test or demonstrate an anaerobic threshold is associated with inferior outcomes after major colorectal surgery. [PDF]

, 2013
BACKGROUND: Surgical patients with poor functional capacity, determined by oxygen consumption at anaerobic threshold (AT) during cardiopulmonary exercise testing (CPET), experience longer hospital stays and worse short- and medium-term survival. However,
Buck, C.P. Challand, C.W. Lai, Carli, Carlisle, Challand, Chase, Copeland, G Minto, J.R. Sneyd, K.B. Hosie, Mayo, Older, Older, Pearse, R.A. Struthers, S Creanor, Shoemaker, Shoemaker, Swart, Tekkis, Visser, Wilson   +22 more
core   +3 more sources

Threats to safe transitions from hospital to home: a consensus study in North West London primary care. [PDF]

, 2019
BACKGROUND: Transitions between healthcare settings are vulnerable points for patients. AIM: To identify key threats to safe patient transitions from hospital to primary care settings.
Ashrafian, H., Darzi, A., Judah, G., Lavelle, M., Lorencatto, F., Markiewicz, O.   +5 more
core   +2 more sources

Frailty in Cardiac Surgery—Assessment Tools, Impact on Outcomes, and Optimisation Strategies: A Narrative Review

Journal of Cardiovascular Development and Disease
Background: Advancements in surgical care have made it possible to offer cardiac surgery to an older and frailer patient cohort. Frailty has been recognised as a prognostic indicator that impacts post-operative recovery and patient outcomes.
Ashwini Chandiramani, Jason M. Ali
doaj   +1 more source

Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale. [PDF]

, 2017
BACKGROUND: Acute decompensated heart failure (ADHF) is a leading cause of hospitalization in older persons in the United States. Reduced physical function and frailty are major determinants of adverse outcomes in older patients with hospitalized ADHF ...
Duncan, Pamela, Eggebeen, Joel D., Hewston, Leigh Ann, Kitzman, Dalane W., Mentz, Robert J., Morgan, Timothy M., O\u27Connor, Christopher M., Pastva, Amy M., Reed, Shelby D., Reeves, Gordon R., Rejeski, W. Jack, Rosenberg, Paul B., Whellan, David J.   +12 more
core   +2 more sources

Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial. [PDF]

, 2015
BACKGROUND & AIMS: Eating habits may influence the life span and the quality of ageing process by modulating inflammation. The RISTOMED project was developed to provide a personalized and balanced diet, enriched with or without nutraceutical compounds ...
Blanc Bisson, C, Bourdel Marchasson, I, Brigidi, P, Buccolini, F, Béné, Mc, Charrouf, Z, D'Alessio, Pa, Donini, Lorenzo Maria, Franceschi, C, Lochs, H, Ostan, R, Pinto, Alessandro, Pryen, F, Spazzafumo, L, Valentini, L   +14 more
core   +3 more sources

Frailty recommendations and guidelines. An evaluation of implementability and critical appraisal of clinical applicability by the ISPRM Frailty Focus Group

The Journal of the International Society of Physical and Rehabilitation Medicine
Objective:. Aging is associated with an increased burden of multimorbidity and disease-related functional loss and disability, widely impacting patients and health care systems.
Eleftheria Antoniadou, MD, PhD, Emanuele Maria Giusti, PhD, Paolo Capodaglio, MD, Dersheng HAN, MD, Francesca Gimigliano, MD, Juan Manuel Guzman, MD, Mooyeon OhPARK, MD, Walter Frontera, MD   +7 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source