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A dynamical model of programmed −1 ribosomal frameshifting
Journal of Theoretical Biology, 2013Programmed -1 ribosomal frameshifting is the most widely used translational recoding mechanism of RNA viruses. How the frameshifting occurs at the slippery sequence on the presence of a downstream mRNA pseudoknot has not been fully understood. Here, we present systematical analysis of the -1 frameshifting that can occur during every transition step in ...
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Evaluating ribosomal frameshifting in CCR5 mRNA decoding
Nature, 2022Yousuf A. Khan +9 more
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HIV pol Expression via a Ribosomal Frameshift
1990The genetic relationship of the gag and pol genes of all retroviruses is approximately the same and the configuration of the protein products of these genes is also strongly conserved (Figure 1) (Weiss et al., 1982). The gag and pol genes are adjacent at the beginning of retroviral transcriptional unit and in most cases the 3′ end of gag and the 5′ end
Alan J. Kingsman +2 more
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Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes
Nature Reviews Molecular Cell Biology, 2023Yutaro Hori, Christoph Engel
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Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy
Signal Transduction and Targeted Therapy, 2021Jian Kang +2 more
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