Results 91 to 100 of about 38,009 (292)

Monocyte / macrophage inflammatory response pathways to combat Francisella infection: possible therapeutic targets?

Frontiers in Cellular and Infection Microbiology, 2014
Francisella tularensis can bypass and suppress host immune responses, even to the point of manipulating immune cell phenotypes and intercellular inflammatory networks. Strengthening these responses such that immune cells more readily identify and destroy
Devyn D Gillette, Susheela eTridandapani, Jonathan P Butchar   +2 more
doaj   +1 more source

Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to Francisella tularensis

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Despite the role of T cell-mediated events in control of intracellular infections, studies from several laboratories have shown that humoral immunity also plays a critical role.
Giuseppe Stefanetti, Nihal A. Okan, A. Fink, Erica Gardner, Dennis L. Kasper   +4 more
semanticscholar   +1 more source

Antibiotic Resistance Genes in Klebsiella pneumoniae and Heavy Metal Contamination in Tilapia (Oreochromis niloticus): A Public Health Risk Assessment in Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Species‐specific 16S‐23S ITS and antibiotic resistance IntI, blaCTX‐M, blaTEM and blaSHV genes of Klebsiella pneumoniae were detected, and most of the isolates were multidrug‐resistant. Target hazard quotient values of Fe for >1 revealed a higher level of hazard index. Target cancer risk values of Fe exceeded the recommended value (<10−4).
M. Sohidullah, Md. Hamidur Rahman, Abu Sayeed, Sadia Rahman, Linta Yesmin, Md. Tazinur Rahman, Muhammad Ashiqul Alam, Md. Jannat Hossain, Md. Imran Chowdhury   +8 more
wiley   +1 more source

Screening for bacterial DNA in the hard tick Hyalomma marginatum (Ixodidae) from Socotra Island (Yemen): detection of Francisella-like endosymbiont

Journal of Entomological and Acarological Research, 2012
Thirty-four adult ticks collected from livestock on Socotra Island (Yemen) were identified as Hyalomma marginatum using traditional morphological characteristics.
M. Montagna, B. Chouaia, F. Pella, M. Mariconti, D. Pistone, M. Fasola, S. Epis   +6 more
doaj   +1 more source

Francisella tularensis Transmission by Solid Organ Transplantation, 20171. [PDF]

, 2019
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Annambhotla, Pallavi, Asad, Shadaba, Aslam, Saima, Basavaraju, Sridhar V, Brown, Jennifer, Burns, Kevin, Carifo, Karen, Dagher, Hikmat N, Fritz, Curtis L, Gonzalez, Anthony, Ham, John, Helsel, Elizabeth, Hinckley, Alison F, Iser, Joseph, Johnson, Michael, Jones, Jefferson M, Kelley, Walter E, Kingry, Luke C, Krafft, Melissa, Kwit, Natalie A, Medina-Garcia, Luis H, Mohler, Kelli, Murua, Christian, Nelson, Christina A, Petersen, Jeannine M, Respicio-Kingry, Laurel, Tularemia in Transplant Recipients Investigation Team, Wiggins, Landon, Zhang, Ying   +28 more
core  

A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory [PDF]

, 2018
We present a multi-scale model of the within-phagocyte, within-host and population-level infection dynamics of Francisella tularensis, which extends the mechanistic one proposed by Wood et al. (2014). Our multi-scale model incorporates key aspects of the
Carruthers, J, Gillard, JJ, Laws, TR, Lythe, G, López-García, M, Molina-París, C   +5 more
core   +3 more sources

Francisella tularensis: FupA mutation contributes to fluoroquinolone resistance by increasing vesicle secretion and biofilm formation

Emerging Microbes and Infections, 2019
Francisella tularensis is the causative agent in tularemia for which the high prevalence of treatment failure and relapse is a major concern. Directed-evolution experiments revealed that acquisition of fluoroquinolone (FQ) resistance was linked to ...
C. Siebert, H. Lindgren, Sabrina Ferré, C. Villers, S. Boisset, J. Pérard, A. Sjöstedt, M. Maurin, C. Brochier-Armanet, Y. Couté, P. Renesto   +10 more
semanticscholar   +1 more source

Effect of High‐Pressure Processing Operating Parameters on Microbial Inactivation and Bioactive Protein Preservation in Bovine Milk: A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora, Caleb Mark, Marie Biondi Ryan, Bishal Barman, Michael Pitino, David C. Dallas   +5 more
wiley   +1 more source

Francisella tularensisvaccines [PDF]

FEMS Immunology & Medical Microbiology, 2007
Francisella tularensis is the causative agent of tularaemia, a disease which occurs naturally in some countries in the northern hemisphere. Recently, there has been a high level of interest in devising vaccines against the bacterium because of the potential for it to be used as a bioterrorism agent.
Kate F, Griffin, Petra C F, Oyston, Richard W, Titball   +2 more
openaire   +2 more sources

Metagenomic profiling of ticks: Identification of novel rickettsial genomes and detection of tick-borne canine parvovirus [PDF]

, 2019
Background: Across the world, ticks act as vectors of human and animal pathogens. Ticks rely on bacterial endosymbionts, which often share close and complex evolutionary links with tick-borne pathogens.
Abdeen, Ziad, Abu Shamma, Omar, Al-Jawabreh, Amer, Ereqat, Suheir, Hall, Holly E., Nasereddin, Abedelmajeed, Pallen, Mark J., Ravi, Anuradha, Taylan Ozkan, Aysegul   +8 more
core   +2 more sources