Frontiers in MicrobiologyFrancisella tularensis secretes tubular outer membrane vesicles (OMVs) that contain a number of immunoreactive proteins as well as virulence factors.
Ivona Pavkova +4 more
doaj +1 more source
Különböző eredetű Francisella tularensis törzsek összehasonlító vizsgálata = Comparative examination of Francisella tularensis strains isolated from different species in Hungary [PDF]
, 2012 Vizsgálataink során Magyarország közel 30 településéről összesen 67 Francisella tularensis törzset gyűjtöttünk, amely révén létrehoztunk egy hazai F. tularensis törzsgyűjteményt.
Makrai, László
core
Metagenomic profiling of ticks: Identification of novel rickettsial genomes and detection of tick-borne canine parvovirus [PDF]
, 2019 Background: Across the world, ticks act as vectors of human and animal pathogens. Ticks rely on bacterial endosymbionts, which often share close and complex evolutionary links with tick-borne pathogens.
Abdeen, Ziad +8 more
core +2 more sources
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
Drug Development Research, Volume 86, Issue 8, December 2025.ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory [PDF]
, 2018 We present a multi-scale model of the within-phagocyte, within-host and population-level infection dynamics of Francisella tularensis, which extends the mechanistic one proposed by Wood et al. (2014). Our multi-scale model incorporates key aspects of the
Carruthers, J +5 more
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Ecology and Evolution, Volume 15, Issue 12, December 2025.This study serves as a proof‐of‐concept, demonstrating that deep shotgun sequencing of a single complex sample—stingless bee larval food—can simultaneously generate multiple genomic resources. From this dataset, we assembled three genomes (a near‐complete bacterium, a draft host mitochondrion, and a fragmented plant chloroplast) with varying ...
Carlos Ueira‐Vieira +6 more
wiley +1 more source
Identification of small RNAs in Francisella tularensis [PDF]
, 2010 Background: Regulation of bacterial gene expression by small RNAs (sRNAs) have proved to be important for many biological processes. Francisella tularensis is a highly pathogenic Gram-negative bacterium that causes the disease tularaemia in humans and ...
Alain Charbit +6 more
core +3 more sources
Putting the Jigsaw Together - A Brief Insight Into the Tularemia
Open Life Sciences, 2015 Tularemia is a debilitating febrile and potentially fatal zoonotic disease of humans and other vertebrates caused by the Gram-negative bacterium Francisella tularensis. The natural reservoirs are small rodents, hares, and possibly amoebas in water.
Kubelkova K., Macela A.
doaj +1 more source
Comparative genomics reveals multiple pathways to mutualism for tick-borne pathogens [PDF]
, 2016 Accelerated pipeline for DNA and amino acid sequences ...
Kelly A. Brayton +2 more
core +3 more sources
Francisella recognition by inflammasomes: differences between Mice and Men
Frontiers in Cellular and Infection Microbiology, 2011 Pathogen recognition by intracellular sensors involves the assembly of a caspase-1 activation machine termed the inflammasome. Intracellular pathogens like Francisella that gain access to the cytosolic detection systems are useful tools to uncover the ...
Mikhail A Gavrilin, Mark D Wewers
doaj +1 more source