Results 101 to 110 of about 27,832 (201)
Bioluminescent Francisella tularensis SCHU S4 enables non-invasive tracking of bacterial dissemination and the evaluation of antibiotics in an inhalational mouse model of tularaemia [PDF]
, 2016 This document is the Accepted Manuscript version of the following article: Hall CA, Flick-Smith HC, Harding SV, Atkins HS, and Titball RW. 2016.
Atkins, Helen +4 more
core +2 more sources
Frontiers in Microbiology, 2016 Francisella tularensis is a Tier 1 bioterror threat and the intracellular pathogen responsible for tularemia in humans and animals. Upon entry into the host, Francisella uses multiple mechanisms to evade killing.
John S Gunn +5 more
doaj +1 more source
Practical guidance for the implementation of the CRISPR genome editing tool in filamentous fungi [PDF]
, 2019 Background: Within the last years, numerous reports described successful application of the CRISPR nucleases Cas9 and Cpf1 for genome editing in filamentous fungi.
Haefner, Stefan +4 more
core +1 more source
The Francisella Type VI Secretion System
Frontiers in Cellular and Infection Microbiology, 2018 Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative agent of the life-threatening zoonotic disease tularemia.
Daniel L. Clemens +2 more
doaj +1 more source
Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008 [PDF]
, 2014 Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable ...
Allue +34 more
core +1 more source
Проблемы особо опасных инфекций, 2016 Objective of the study is to assess diagnostic efficiency of PCR kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF», when performing analysis of biological samples from animals with experimental tularemia, as compared to other
A. M. Senichkina +3 more
doaj +1 more source
Francisella tularensis Schu S4 lipopolysaccharide core sugar and o-antigen mutants are attenuated in a mouse model of tularemia [PDF]
, 2014 The virulence factors mediating Francisella pathogenesis are being investigated, with an emphasis on understanding how the organism evades innate immunity mechanisms.
Apicella, Michael A +6 more
core +2 more sources
PLoS ONE, 2013 Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms.
Amanda J Griffin +4 more
doaj +1 more source
Border patrol gone awry: Lung NKT cell activation by Francisella tularensis exacerbates tularemia-like disease [PDF]
, 2015 The respiratory mucosa is a major site for pathogen invasion and, hence, a site requiring constant immune surveillance. The type I, semi-invariant natural killer T (NKT) cells are enriched within the lung vasculature.
Boyd, Kelli L +8 more
core +5 more sources
BMC Microbiology, 2012 Background Recent advances in sequencing technologies offer promising tools for generating large numbers of genomes, larger typing databases and improved mapping of environmental bacterial diversity.
Ahlinder Jon +7 more
doaj +1 more source