Results 101 to 110 of about 38,009 (292)

Francisella requires dynamic type VI secretion system and ClpB to deliver effectors for phagosomal escape

open access: yesNature Communications, 2017
Francisella tularensis is an intracellular pathogen that causes the fatal zoonotic disease tularaemia. Critical for its pathogenesis is the ability of the phagocytosed bacteria to escape into the cell cytosol.
Maj Brodmann   +3 more
semanticscholar   +1 more source

Disrupting Viral Persistence: CRISPR/Cas9‐Based Strategies for Hepatitis B and C Treatment, and Challenges

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Hepatitis B and C viruses (HBV and HCV) remain among the leading causes of liver disease worldwide. Current antiviral drugs, such as nucleotide analogues (NAs), can reduce the replication of new HBV and HCV infections but cannot completely eliminate chronic infections.
Meng‐Fan Li   +3 more
wiley   +1 more source

The complex amino acid diet of Francisella in infected macrophages

open access: yesFrontiers in Cellular and Infection Microbiology, 2015
Francisella tularensis, the agent of the zoonotic disease tularemia, is a highly infectious bacterium for a large number of animal species and can be transmitted to humans by various means.
Alain eCharbit
doaj   +1 more source

Francisella-like endosymbionts, potentially harmful to human health, are transported by the universally distributed species of the ciliate Euplotes. [PDF]

open access: yes, 2016
Genome analyses of wild-type strains of two ecologically separated Euplotes species, E. raikovi living in temperate sea waters and E. petzi living in the polar seas, revealed that both host bacteria in their cytoplasm. These bacteria have been identified
Di Giuseppe, G   +8 more
core  

Bioluminescent Francisella tularensis SCHU S4 enables non-invasive tracking of bacterial dissemination and the evaluation of antibiotics in an inhalational mouse model of tularaemia [PDF]

open access: yes, 2016
This document is the Accepted Manuscript version of the following article: Hall CA, Flick-Smith HC, Harding SV, Atkins HS, and Titball RW. 2016.
Atkins, Helen   +4 more
core   +2 more sources

Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against Francisella novicida

open access: yesJournal of Immunology, 2018
The DNA sensor absent in melanoma 2 (AIM2) forms an inflammasome complex with ASC and caspase-1 in response to Francisella tularensis subspecies novicida infection, leading to maturation of IL-1β and IL-18 and pyroptosis.
Qifan Zhu   +4 more
semanticscholar   +1 more source

Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization

open access: yesCase Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
We present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Allianna Mitchell   +7 more
wiley   +1 more source

Genetic Manipulation of Francisella Tularensis [PDF]

open access: yesFrontiers in Microbiology, 2011
Francisella tularensis is a facultative intracellular pathogen that causes the disease tularemia. F. tularensis subsp. tularensis causes the most severe disease in humans and has been classified as a Category A select agent and potential bioweapon.
Zogaj, Xhavit, Klose, Karl E.
openaire   +3 more sources

Comparative genomics reveals multiple pathways to mutualism for tick-borne pathogens [PDF]

open access: yes, 2016
Accelerated pipeline for DNA and amino acid sequences ...
Kelly A. Brayton   +2 more
core   +3 more sources

The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella

open access: yesNature Communications, 2017
The enzyme fructose-bisphosphate aldolase occupies a central position in glycolysis and gluconeogenesis pathways. Beyond its housekeeping role in metabolism, fructose-bisphosphate aldolase has been involved in additional functions and is considered as a ...
Jason Ziveri   +11 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy