Results 111 to 120 of about 38,009 (292)
Regulation of Francisella Tularensis Virulence [PDF]
Frontiers in Microbiology, 2011 Francisella tularensis is one of the most virulent bacteria known and a Centers for Disease Control and Prevention Category A select agent. It is able to infect a variety of animals and insects and can persist in the environment, thus Francisella spp. must be able to survive in diverse environmental niches. However, F.
Shipan eDai +7 more
openaire +3 more sources
Practical guidance for the implementation of the CRISPR genome editing tool in filamentous fungi [PDF]
, 2019 Background: Within the last years, numerous reports described successful application of the CRISPR nucleases Cas9 and Cpf1 for genome editing in filamentous fungi.
Haefner, Stefan +4 more
core +1 more source
Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis [PDF]
, 2022 Roberto De Pascalis +8 more
openalex +1 more source
Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis
PLoS ONE, 2019 Francisella tularensis is a Gram-negative bacterium responsible for causing tularemia in the northern hemisphere. F. tularensis has long been developed as a biological weapon due to its ability to cause severe illness upon inhalation of as few as ten ...
Zhuo Ma +7 more
semanticscholar +1 more source
Rombencephalitis Caused by Francisella tularensis [PDF]
Journal of Clinical Microbiology, 2013 ABSTRACT Common presentations of tularemia include pneumonia and ulceroglandular, oropharyngeal, or typhoidal disease. Neuromeningeal involvement is extremely rare. We report a case of a severe rhombencephalitis due to Francisella tularensis .
Barbaz, Mathilde +7 more
openaire +3 more sources
Iranian Journal of Microbiology, 2019 Background and Objectives: Francisella tularensis has a wide distribution in northern hemisphere of the world. Up to now, there was little information about the Francisella spp. situation in the environmental samples in Iran.
Mahdi Rohani +5 more
doaj +1 more source
Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008 [PDF]
, 2014 Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable ...
Allue +34 more
core +1 more source
Nature Communications, 2019 Pulmonary immune control is crucial for protection against pathogens. Here we identify a pathway that promotes host responses during pulmonary bacterial infection; the expression of CD200 receptor (CD200R), which is known to dampen pulmonary immune ...
J. Casulli +14 more
semanticscholar +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
Drug Development Research, Volume 86, Issue 8, December 2025.ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Interactions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium. [PDF]
PLoS ONE, 2015 Francisella tularensis is classified as a Tier 1 select agent by the CDC due to its low infectious dose and the possibility that the organism can be used as a bioweapon.
Matthew Faron +4 more
doaj +1 more source