Results 51 to 60 of about 60,935 (313)

Antioxidant Activity and Polyphenolic Content of North Macedonian Wines

Applied Sciences, 2020
The purpose of this study was to evaluate comparatively the polyphenolic content and the antioxidant activity of selected regional red and white wine varieties, produced in the Republic of North Macedonia.
Katerina Mitrevska, Spyros Grigorakis, Sofia Loupassaki, Antony C. Calokerinos   +3 more
doaj   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Sempervivum davisii: phytochemical composition, antioxidant and lipase-inhibitory activities

Pharmaceutical Biology, 2017
Context: Sempervivum davisii Muirhead (Crassulaceae) is a traditional medicinal herb from Eastern Anatolia. To date the composition of phytochemicals and physiological properties of this herb were not subjected to any research.
Yusuf Uzun, Abdullah Dalar, Izabela Konczak   +2 more
doaj   +1 more source

A Methodology for Deciphering the Transmembrane Resistance Variability of Supported Lipid Bilayers

Advanced Science, EarlyView.
This work shows that transmembrane resistance variability, due to lipid packing defects, can be quantified by analysing the dielectric properties of Supported Lipid Bilayers. The proposed methodology provides an analytical tool for optimizing SLB design with improved stability and functionality for bioelectronic and biomimetic applications. Abstract In
Aristea Pavlou, Debdatta Panigrahi, Somayeh Kashani, Anna‐Maria Pappa, Fabrizio Torricelli, Paul W.M. Blom, Paschalis Gkoupidenis   +6 more
wiley   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

Advanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo, Leonardo Barzaghi, Yuan Shen, Edoardo Bellini, Emanuele Martini, Serena Magni, Sara Barozzi, Fabrizio Orsenigo, Dario Parazzoli, Galina V. Beznoussenko, Jasmin Di Franco, Fabian Krautgasser, Jasmin Kaivola, Mario Cinquanta, Alessandro Lazzarin, Sara Sigismund, Johanna Ivaska, Roberto Cerbino, Giorgio Scita   +18 more
wiley   +1 more source

Determination of Monoamine Oxidase Inhibition and Antioxidant Effects of Various Herbal Teas

Trakya University Journal of Natural Sciences, 2017
The therapeutic properties of fruit teas are due to the polyphenolic flavonoids they contain. Compounds inhibiting the flavoenzyme monoamine oxidase (EC 1.4.3.4, MAO) are known to be used as medicines in treatment of neurodegenerative disorders such as ...
Başak Yüce Dursun
doaj   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

ANTIOXIDANT ACTIVITY DUAL METHODS OF DIFFERENT POLARITY EXTRACTS OF STEM OF SOLANUM NIGRUM L. GROWING IN ALGERIA

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2021
The purpose of this study is to evaluate the antioxidants properties and phenolic and flavonoid contents of Solanum nigrum L. growing in El-Oued region (south east of Algeria). The different polarity extracts chloroform (CHCl3), ethyl acetate (AcOEt) and
IMANE GUEDIRI , CHERIFA BOUBEKRI , OUANISSA SMARA   +2 more
doaj  

Distributed Actin Turnover in the Lamellipodium and FRAP Kinetics [PDF]

Biophysical Journal, 2013
Studies of actin dynamics at the leading edge of motile cells with single-molecule speckle (SiMS) microscopy have shown a broad distribution of EGFP-actin speckle lifetimes and indicated actin polymerization and depolymerization over an extended region.
Smith, Matthew B., Kiuchi, Tai, Watanabe, Naoki, Vavylonis, Dimitrios   +3 more
openaire   +2 more sources

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source