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Free-Water Correction DTI-Based Tractography in Brain Tumor Surgery: Assessment With Functional and Electrophysiological Mapping of the White Matter

open access: yesActa Neurochirurgica, 2023
Peritumoral edema prevents fiber tracking from diffusion tensor imaging (DTI). A free-water correction may overcome this drawback, as illustrated in the case of a patient undergoing awake surgery for brain metastasis. The anatomical plausibility and accuracy of tractography with and without free-water correction were assessed with functional mapping ...
Fabien Almairac   +2 more
exaly   +4 more sources
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Characterizing Peritumoral Tissue Using DTI-Based Free Water Elimination

Lecture Notes in Computer Science, 2019
Finding an accurate microstructural characterization of the peritumoral region is essential to distinguish between edema and infiltration, enabling the distinction between tumor types, and to improve tractography in this region. Characterization of healthy versus pathological tissue is a key concern when modeling tissue microstructure in the ...
Steven Brem   +2 more
exaly   +3 more sources

T2 relaxometry based CSF fraction (CSFF) mapping is a better biomarker for brain drainage pathology than DTI-based free water (DTI-FW) mapping

ISMRM Annual Meeting, 2023
We compared two free water methods, T2 relaxometry-based CSFF and DTI-based DTI-FW, by associating them with age, cognitive score RAVLT, amyloid beta deposition from PiB SUVr, tau deposition from MK6240, aqueduct CSF flow from PC-MRI and ventricle CSF clearance from MK-PET. Results show that CSFF outperforms DTI-FW in most relation pairs.
Liangdong Zhou, Thanh Nguyen, Yi Li
openaire   +1 more source

Free Water Elimination and Mapping From Diffusion MRI

open access: yesMagnetic Resonance in Medicine, 2009
Relating brain tissue properties to diffusion tensor imaging (DTI) is limited when an image voxel contains partial volume of brain tissue with free water, such as cerebrospinal fluid or edema, rendering the DTI indices no longer useful for describing the
Yaniv Assaf   +2 more
exaly   +2 more sources

Mediation pathways and complementary roles of DTI-ALPS and free water fraction in glymphatic impairment and cognitive decline

Journal of Alzheimer’s Disease
Background Glymphatic system dysfunction is linked to cognitive decline in dementia continuum. Diffusion magnetic resonance imaging markers like the Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS) index and whole-brain free water (FW) fraction allow non-invasive evaluation of glymphatic ...
Yi-Chia Wei   +7 more
openaire   +2 more sources

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