Results 131 to 140 of about 10,072 (149)
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ISMRM Annual Meeting, 2023
We compared two free water methods, T2 relaxometry-based CSFF and DTI-based DTI-FW, by associating them with age, cognitive score RAVLT, amyloid beta deposition from PiB SUVr, tau deposition from MK6240, aqueduct CSF flow from PC-MRI and ventricle CSF clearance from MK-PET. Results show that CSFF outperforms DTI-FW in most relation pairs.
Liangdong Zhou, Thanh Nguyen, Yi Li
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We compared two free water methods, T2 relaxometry-based CSFF and DTI-based DTI-FW, by associating them with age, cognitive score RAVLT, amyloid beta deposition from PiB SUVr, tau deposition from MK6240, aqueduct CSF flow from PC-MRI and ventricle CSF clearance from MK-PET. Results show that CSFF outperforms DTI-FW in most relation pairs.
Liangdong Zhou, Thanh Nguyen, Yi Li
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ISMRM Annual Meeting
Major depressive disorder (MDD) is a common mental disease with unclear pathophysiology. Herein, we explored the differences in the whole-brain gray matter free-water axial diffusivity (AD) and mean diffusivity (MD) values between MDD patients and healthy controls using free-water DTI.
Xuecong Lin +9 more
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Major depressive disorder (MDD) is a common mental disease with unclear pathophysiology. Herein, we explored the differences in the whole-brain gray matter free-water axial diffusivity (AD) and mean diffusivity (MD) values between MDD patients and healthy controls using free-water DTI.
Xuecong Lin +9 more
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ISMRM Annual Meeting
The objective of this study was to explore the relationship between cognitive impairment and free-water elimination DTI (FWE-DTI) metrics in patients with intracranial vascular occlusion disease (IVOD) and transient ischemic attack (TIA). 22 IVOD with TIA patients were tested with cognitive scales and scanned using a 3T echo-planar imaging sequence ...
Siyuan Fang +5 more
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The objective of this study was to explore the relationship between cognitive impairment and free-water elimination DTI (FWE-DTI) metrics in patients with intracranial vascular occlusion disease (IVOD) and transient ischemic attack (TIA). 22 IVOD with TIA patients were tested with cognitive scales and scanned using a 3T echo-planar imaging sequence ...
Siyuan Fang +5 more
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Journal of Alzheimer’s Disease
Background Glymphatic system dysfunction is linked to cognitive decline in dementia continuum. Diffusion magnetic resonance imaging markers like the Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS) index and whole-brain free water (FW) fraction allow non-invasive evaluation of glymphatic ...
Yi-Chia Wei +7 more
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Background Glymphatic system dysfunction is linked to cognitive decline in dementia continuum. Diffusion magnetic resonance imaging markers like the Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS) index and whole-brain free water (FW) fraction allow non-invasive evaluation of glymphatic ...
Yi-Chia Wei +7 more
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ISMRM Annual Meeting
Motivation: Microstructural brain abnormalities are well documented in people with HIV (PWH). However, the effects of long-term marijuana use on white matter integrity are less established. Goal(s): The goal of this study is to examine if HIV infection and chronic marijuana use have differential or additive effect on white matter abnormalities ...
Teddy Salan +8 more
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Motivation: Microstructural brain abnormalities are well documented in people with HIV (PWH). However, the effects of long-term marijuana use on white matter integrity are less established. Goal(s): The goal of this study is to examine if HIV infection and chronic marijuana use have differential or additive effect on white matter abnormalities ...
Teddy Salan +8 more
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ISMRM Annual Meeting
Motivation: The study aims to address the limitations of standard DTI in detecting subtle white matter alterations in individuals with mild cognitive impairment (MCI). Goal(s): Compare standard vs. free-water (fw) corrected tractography for MCI assessment.
Maurizio Bergamino +2 more
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Motivation: The study aims to address the limitations of standard DTI in detecting subtle white matter alterations in individuals with mild cognitive impairment (MCI). Goal(s): Compare standard vs. free-water (fw) corrected tractography for MCI assessment.
Maurizio Bergamino +2 more
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ISMRM Annual Meeting
Motivation: Diffusion tensor imaging in the spinal cord is compromised by partial volume effects from surrounding cerebrospinal fluid. Free-water elimination shows promise of partial volume effect reduction in the brain but has never been tested on the human spinal cord.
Alma Blombäck +3 more
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Motivation: Diffusion tensor imaging in the spinal cord is compromised by partial volume effects from surrounding cerebrospinal fluid. Free-water elimination shows promise of partial volume effect reduction in the brain but has never been tested on the human spinal cord.
Alma Blombäck +3 more
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Journal of Alzheimer’s Disease
Background: Dementia is characterized by a cognitive decline in memory and other domains that lead to functional impairments. As people age, subjective memory complaints (SMC) become common, where individuals perceive cognitive decline without objective deficits on assessments.
Maurizio, Bergamino +6 more
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Background: Dementia is characterized by a cognitive decline in memory and other domains that lead to functional impairments. As people age, subjective memory complaints (SMC) become common, where individuals perceive cognitive decline without objective deficits on assessments.
Maurizio, Bergamino +6 more
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