Results 1 to 10 of about 1,362 (166)

Evaluation and Interpretation of DTI-ALPS, a Proposed Surrogate Marker for Glymphatic Clearance, in a Large Population-Based Sample

Alzheimer's Research and Therapy
Background The diffusion tensor imaging along perivascular spaces index (DTI-ALPS), which measures diffusivity in the perivascular spaces along the medullary veins, has gained popularity and controversy as a surrogate marker of glymphatic clearance.
Petrice M Cogswell, Sheelakumari Raghavan, Scott A Przybelski   +2 more
exaly   +2 more sources

Reconsideration of the DTI-ALPS index as a glymphatic surrogate: disease-specific findings in small vessel disease due to cerebral amyloid angiopathy or arteriolosclerosis [PDF]

Frontiers in Aging Neuroscience
ObjectivesTo explore the disease-specific performance of diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index in cerebral amyloid angiopathy (CAA) and arteriolosclerosis CSVD (aCSVD).MethodsWe retrospectively enrolled probable ...
Yaping Zhou, Xingqi Pan, Ziyi Xia, Yuhui Sha, Gan Sun, Fei Han, Ming Yao, Lixin Zhou, Liyun Tu, Feng Feng, Joanna M. Wardlaw, Yi-Cheng Zhu, Jun Ni   +12 more
doaj   +2 more sources

DTI-ALPS as a marker of glymphatic function: Review of the literature findings, methodology, and interpretation [PDF]

NeuroImage: Reports
The glymphatic system (GS) describes how the brain clears toxins and metabolic waste. Accumulation of these elements can contribute to onset and severity of brain disorders, so the importance of measuring the GS is vital to understanding how neurological
Jerome J. Maller, Vincent A. Magnotta
doaj   +2 more sources

Multimodal MRI of choroid plexus volume, DTI-ALPS, and white matter microstructure in type 2 diabetes mellitus [PDF]

Frontiers in Medicine
ObjectiveTo investigate differences in choroid plexus volume (CPV), diffusion tensor image analysis along the perivascular space (DTI-ALPS) indices, peak width of skeletonized mean diffusivity (PSMD), and Mini-Mental State Examination (MMSE) scores ...
Minghui Mao, Minghui Mao, Minghui Mao, Linghan Chen, Linghan Chen, Juan Xia, Juan Xia, Taipeng Zeng, Taipeng Zeng, Hao Huang, Jianfeng Chu, Liyuan Fu, Liyuan Fu   +12 more
doaj   +2 more sources

Lateralized glymphatic system impairment in acute ischemic stroke: a DTI–ALPS study of upper limb motor function [PDF]

Frontiers in Neurology
BackgroundThe glymphatic system (GS) is a brain-specific waste clearance pathway essential for maintaining cerebral homeostasis. Diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) provides a non-invasive means of evaluating GS ...
Zilong Zhu, Zilong Zhu, Zhilong Zhao, Lihua Zhou, Junfeng Xiong, Tianrui Zhang, Chunling Wei, Jianbin Zhang, Jianbin Zhang   +8 more
doaj   +2 more sources

Non-invasive assessment of glymphatic dysfunction in middle cerebral artery stenosis based on DTI-ALPS and ro-ALPS [PDF]

Frontiers in Neurology
BackgroundMiddle cerebral artery stenosis (MCA-S) impairs cerebral perfusion and vascular pulsatility, potentially disrupting cerebrospinal fluid dynamics.
Yidi Zhu, Luoyu Wang, Liqing Zhang, Xue Tang, Maoling Liu, Qingqing Wen, Darong Zhu, Han Zhang, Xiufang Xu, Zhongxiang Ding   +9 more
doaj   +2 more sources

Glymphatic Dysfunction in Patients With End-Stage Renal Disease

Frontiers in Neurology, 2022
BackgroundWe aimed to compare glymphatic dysfunction between patients with end-stage renal disease (ESRD) and healthy controls and analyze the correlation between the glymphatic function and clinical characteristics using the diffusion tensor image ...
Chang Min Heo, Won Ho Lee, Bong Soo Park, Yoo Jin Lee, Sihyung Park, Yang Wook Kim, Dong Ah Lee, Byeong Cheol Yoo, Kang Min Park   +8 more
doaj   +1 more source

Glymphatic system dysfunction in temporal lobe epilepsy patients with hippocampal sclerosis

Epilepsia Open, 2022
Objective This study aimed to evaluate glymphatic system function in temporal lobe epilepsy (TLE) patients with hippocampal sclerosis (HS) in comparison to healthy controls, using diffusion tensor imaging (DTI)‐analysis along the perivascular space (ALPS)
Dong Ah Lee, Bong Soo Park, Junghae Ko, Si Hyung Park, Yoo Jin Lee, Il Hwan Kim, Jin Han Park, Kang Min Park   +7 more
doaj   +1 more source

Dysfunction of the glymphatic system in childhood absence epilepsy

Frontiers in Neuroscience, 2023
ObjectiveThis study aimed to evaluate the glymphatic system in childhood absence epilepsy (CAE) using diffusion tensor image analysis along the paravascular space (DTI-ALPS) index.
Wanqing Pu, Shanzhen Wei, Mengdi Qiu, Xiaoyu Chen, Wenwei Zou, Yingchao Ge, Wenchao Qiu   +6 more
doaj   +1 more source

Glymphatic system dysfunction in patients with early chronic kidney disease

Frontiers in Neurology, 2022
IntroductionIt is a recent finding that glymphatic system dysfunction contributes to various neurological problems. The purpose of this research was to assess the function of the glymphatic system in neurologically asymptomatic early chronic kidney ...
Chang Min Heo, Dong Ah Lee, Kang Min Park, Yoo Jin Lee, Sihyung Park, Yang Wook Kim, Junghae Ko, Byeong Cheol Yoo, Bong Soo Park   +8 more
doaj   +1 more source