Results 51 to 60 of about 271,727 (264)

An Integral Equation Approach to the Irreversible Investment Problem with a Finite Horizon

open access: yesMathematics, 2020
This paper studies an irreversible investment problem under a finite horizon. The firm expands its production capacity in irreversible investments by purchasing capital to increase productivity.
Junkee Jeon, Geonwoo Kim
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Quenching phenomenon of singular parabolic problems with L^1 initial data

open access: yesElectronic Journal of Differential Equations, 2016
We extend some previous existence results for quenching type parabolic problems involving a negative power of the unknown in the equation to the case of merely integrable initial data. We show that $L^1(\Omega)$ is the suitable framework to obtain the
Anh Nguyen Dao   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Remarks on positive and free boundary solutions to a singular equation

open access: yesRevista Integración, 2010
The equation −∆u = χ{u>0} − 1 uβ +λf(x, u)  in Ω with Dirichlet boundary condition on ∂Ω has a maximal solution uλ ≥ 0 for every λ > 0. For λ less than a constant λ ∗ the solution vanishes inside the domain, and for λ > λ∗ the solution is ...
Juan Dávila, Marcelo Montenegro
doaj  

The existence of axially symmetric stationary fluids with gravity

open access: yesAdvances in Nonlinear Analysis
We establish a theoretical framework for the existence of axially symmetric stationary fluids with gravity within nozzles of finite height. The main focus is on the free streamline theory in axially symmetric fluids under the influence of gravity, with ...
Zhang Fan
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A priori estimates for free boundary fluid-structure interaction models of magnetohydrodynamic flows with diffusion

open access: yesAdvances in Nonlinear Analysis
A 3D free-boundary nonlinear fluid-structure interaction (FSI) problem in which the elastic body fully immersed in the magnetofluid is considered. The fluid is modeled by the Magnetohydrodynamic (MHD) equations with diffusion while the structure is ...
Shen Lin, Wang Shu
doaj   +1 more source

Periodic structures on liquid-phase smectic A, nematic and isotropic free surfaces

open access: yesBeilstein Journal of Nanotechnology, 2018
The free boundary of smectic A (SmA), nematic and isotropic liquid phases were studied using a polarized optical microscope, an interferometric surface structure analyzer (ISSA), an atomic force microscope (AFM) and a scanning near-field optical ...
Anna N. Bagdinova   +5 more
doaj   +1 more source

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