Results 61 to 70 of about 271,727 (264)

Numerical Solution of a Free Boundary Problem from Heat Transfer by the Second Kind Chebyshev Wavelets [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2019
In this paper we reduce a free boundary problem from heat transfer to a weakly Singular Volterra  integral equation of the first kind. Since the first kind integral equation is ill posed, and an appropriate method for such ill posed problems is based on ...
Bahman Babayar-Razlighi
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Spreading solutions for a reaction diffusion equation with free boundaries in time-periodic environmen

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we consider a reaction diffusion equation with free boundaries in a time-periodic environment. Such models can be used to describe the spreading of a new or invasive species over a one-dimensional habitat, with the free boundaries ...
Fang Li, Junfan Lu
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Global Existence of Solutions to a Free Boundary Problem for Viscous Incompressible Magnetohydrodynamics for Small Data

open access: yesMathematics
The motion of viscous incompressible magnetohydrodynamics (MHD) is considered in a domain that is bounded by a free surface. The motion interacts through the free surface with an electromagnetic field located in a domain exterior to the free surface and ...
Piotr Kacprzyk   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

A Diffusive Predator-Prey System with a Free Boundary

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki
In this paper, we consider a problem with a free boundary for a diffusive predator-prey system in the onedimensional case. Nonlinear problems with free boundary are studied using a method based on constructing a priori estimates.
Rasulov, M.S., Jamoldinova, Sh.M.
doaj   +1 more source

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