Results 71 to 80 of about 1,969,022 (331)

A Wolbachia infection model with free boundary

Journal of Biological Dynamics, 2020
Scientists have been seeking ways to use Wolbachia to eliminate the mosquitoes that spread human diseases. Could Wolbachia be the determining factor in controlling the mosquito-borne infectious diseases? To answer this question mathematically, we develop
Yunfeng Liu, Zhiming Guo, Mohammad El Smaily, Lin Wang   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The existence of axially symmetric stationary fluids with gravity

Advances in Nonlinear Analysis
We establish a theoretical framework for the existence of axially symmetric stationary fluids with gravity within nozzles of finite height. The main focus is on the free streamline theory in axially symmetric fluids under the influence of gravity, with ...
Zhang Fan
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Well-posedness for physical vacuum free boundary problem of compressible Euler equations with time-dependent damping

Advances in Nonlinear Analysis
In this article, we consider the well-posedness of the local smooth solutions to the physical vacuum free boundary problem of the cylindrical symmetric Euler equations with time-dependent damping −μ(1+t)λρu-\frac{\mu }{{(1+t)}^{\lambda }}\rho {\bf{u}}, μ>
Li Haitong, Mai La-Su, Wang Shiyu
doaj   +1 more source

Global Existence of Solutions to a Free Boundary Problem for Viscous Incompressible Magnetohydrodynamics for Small Data

Mathematics
The motion of viscous incompressible magnetohydrodynamics (MHD) is considered in a domain that is bounded by a free surface. The motion interacts through the free surface with an electromagnetic field located in a domain exterior to the free surface and ...
Piotr Kacprzyk, Wojciech M. Zaja̧czkowski   +1 more
doaj   +1 more source

Dynamics of an epidemic model with advection and free boundaries

Mathematical Biosciences and Engineering, 2019
This paper deals with the propagation dynamics of an epidemic model, which is modeled by a partially degenerate reaction-diffusion-advection system with free boundaries and sigmoidal function.
Meng Zhao, Wan-Tong Li , Yang Zhang
doaj   +1 more source

An Integral Equation Approach to the Irreversible Investment Problem with a Finite Horizon

Mathematics, 2020
This paper studies an irreversible investment problem under a finite horizon. The firm expands its production capacity in irreversible investments by purchasing capital to increase productivity.
Junkee Jeon, Geonwoo Kim
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source