Results 51 to 60 of about 566,112 (285)

Imaging Molecular Structure through Femtosecond Photoelectron Diffraction on Aligned and Oriented Gas-Phase Molecules [PDF]

, 2014
This paper gives an account of our progress towards performing femtosecond time-resolved photoelectron diffraction on gas-phase molecules in a pump-probe setup combining optical lasers and an X-ray Free-Electron Laser.
Adolph, Marcus, Anielski, Denis, Aquila, Andrew, Bari, Sadia, Boll, Rebecca, Bomme, Cedric, Bostedt, Christoph, Bozek, John D., Chapman, Henry N., Christensen, Lauge, Coffee, Ryan, Coppola, Niccola, De, Sankar, Decleva, Piero, Epp, Sascha W., Erk, Benjamin, Filsinger, Frank, Foucar, Lutz, Gorkhover, Tais, Gumprecht, Lars, Hoemke, Andre, Holmegaard, Lotte, Johnsson, Per,, Kienitz, Jens S., Kierspel, Thomas, Krasniqi, Faton, Kuehnel, Kai-Uwe, Kuepper, Jochen, Lund University., Maurer, Jochen, Messerschmidt, Marc, Moshammer, Robert, Mueller, Nele L. M., Rolles, Daniel, Rouzee, Arnaud, Rudek, Benedikt, Rudenko, Artem, Savelyev, Evgeny, Schlichting, Ilme, Schmidt, Carlo, Scholz, Frank, Schorb, Sebastian, Schulz, Joachim, Seltmann, Joern, Stapelfeldt, Henrik, Stener, Mauro, Stern, Stephan, Techert, Simone, Thogersen, Jan, Trippel, Sebastian, Ullrich, Joachim, Viefhaus, Jens, Vrakking, Marc   +52 more
core   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Calculation of x-ray scattering patterns from nanocrystals at high x-ray intensity

Structural Dynamics, 2016
We present a generalized method to describe the x-ray scattering intensity of the Bragg spots in a diffraction pattern from nanocrystals exposed to intense x-ray pulses. Our method involves the subdivision of a crystal into smaller units.
Malik Muhammad Abdullah, Zoltan Jurek, Sang-Kil Son, Robin Santra   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Hard x-ray or gamma ray laser by a dense electron beam

, 2012
A coherent x-ray or gamma ray can be created from a dense electron beam propagating through an intense laser undulator. It is analyzed by using the Landau damping theory which suits better than the conventional linear analysis for the free electron laser,
Moon, S. J., Son, S.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Operation of Photo Electron Spectrometers for Non-Invasive Photon Diagnostics at the European X-Ray Free Electron Laser

Applied Sciences
Angle-resolved photoelectron spectrometers with microchannel plate detectors and fast digitizer electronics are versatile and powerful devices for providing non-invasive single-shot photon diagnostics at a MHz repetition rate X-ray free-electron lasers ...
Joakim Laksman, Florian Dietrich, Theophilos Maltezopoulos, Jia Liu, Danilo Enoque Ferreira de Lima, Natalia Gerasimova, Ivars Karpics, Naresh Kujala, Philipp Schmidt, Suren Karabekyan, Svitozar Serkez, Jan Grünert   +11 more
doaj   +1 more source

Observation and Control of Laser-Enabled Auger Decay

, 2017
Single photon laser enabled Auger decay (spLEAD) has been redicted theoretically [Phys. Rev. Lett. 111, 083004 (2013)] and here we report its first experimental observation in neon. Using coherent, bichromatic free-electron laser pulses, we have detected
Ahmadi, H., Allaria, E., Callegari, C., Carpeggiani, P., Comby, A., Csizmadia, T., Ferrari, E., Finetti, P., Fischer, A., Gauthier, D., Giannessi, L., Iablonskyi, D., Ishikawa, Kenichi L., Kheifets, A. S., Kuehn, S., Mazza, T., Meyer, M., Ovcharenko, E., Plekan, O., Prince, K. C., Reduzzi, M., Roussel, E., Sansone, G., Ueda, K.   +23 more
core   +1 more source

Thermoreflectance Detection of Point Defects Resulting from Focused Ion Beam Milling

Advanced Engineering Materials, EarlyView.
Focused ion beam (FIB) milling is a common tool for nanoscale material processing, however irradiation damage, redeposition, and contamination can occur. We use several characterization tools to show FIB‐induced effects beyond 1 mm from the milled area.
Thomas W. Pfeifer, Eric R. Hoglund, Anton V. Ievlev, Patrick E. Hopkins   +3 more
wiley   +1 more source

Novel correction procedure for compensating thermal contraction errors in the measurement of the magnetic field of superconducting undulator coils in a liquid helium cryostat

Journal of Synchrotron Radiation
Superconducting undulators (SCUs) can offer a much higher on-axis undulator field than state-of-the-art cryogenic permanent-magnet undulators with the same period and vacuum gap.
Barbara Marchetti, Johann Baader, Sara Casalbuoni, Grigory Yakopov, Mikhail Yakopov   +4 more
doaj   +1 more source