Results 211 to 220 of about 333,221 (246)

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielmann, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

Retraction Note: ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines. [PDF]

Sci Rep
Lin G, Zhu S, Wu Y, Song C, Wang W, Zhang Y, Chen YL, He Z.   +7 more
europepmc   +1 more source

Comparison of Methods to Determine the Free Fatty Acid Content of Butter

, 1969
E.S. Humbert, R.C. Lindsay
openalex   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

Triple-Gene Overexpression of the AcrA-AcrB-TolC Transporter System in Synechocystis sp. PCC 6803 Contributes to a Higher Secretion of Free Fatty Acids in Response to Nitrogen Shortage and Salt Stress. [PDF]

Int J Mol Sci
Eungrasamee K, Lindblad P, Jantaro S.
europepmc   +1 more source

EFFECTS OF VASOPRESSIN ON THE PLASMA CONCENTRATION OF FREE FATTY ACIDS AND IN VITRO OXYGEN CONSUMPTION OF TISSUES OF THE RAT

, 1966
Shinji Itoh, Morio Tsukada, Akimasa Okuno, Tadashi Yoshinari   +3 more
openalex   +2 more sources

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Small-angle x-ray scattering investigation of the integration of free fatty acids in polysorbate 20 micelles. [PDF]

Biophys J
Ehrit J, Gräwert TW, Göddeke H, Konarev PV, Svergun DI, Nagel N.   +5 more
europepmc   +1 more source

Fatty Acids of Hair Lipids of Germ Free and Germ Exposed Rats**From the Division of Dermatology, University of Minnesota Medical School, Minneapolis, Minnesota 55455.

, 1965
Q.T. Smith, Ramon M. Fusaro, David Grande   +2 more
openalex   +1 more source

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

Advanced Science, EarlyView.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng, Ge Hu, Shenbo Zhang, Rui Lv, Limeng Sun, Zhe Zhang, Zhengyu Jin, Yanyan Wu, Chen Huang, Lu Ye, Zhe‐Sheng Chen, Yunlu Feng, Aiming Yang, Zhiwei Wang, Huadan Xue   +14 more
wiley   +1 more source