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Free radical scavengers in anaesthesiology and critical care. [PDF]
Indian J Anaesth, 2012 Free radicals are highly reactive and unstable compounds. These highly reactive molecules cause oxidative damage to cellular components such as DNA, proteins and lipids. They play central role in the mechanism of cell injury and cell death. Free radical scavengers either prevent these reactive species from being formed, or remove them before they can ...
Hatwalne MS.
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Captopril: a free radical scavenger. [PDF]
British Journal of Clinical Pharmacology, 1989 The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopril is a free radical scavenger and we suggest that
Chopra, M. +6 more
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Scavenging Effects of Dexrazoxane on Free Radicals [PDF]
Journal of Clinical Biochemistry and Nutrition, 2010 Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation ...
Zhao Yan, Zhao Baolu, Zhang Junjing
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Free radical scavenging activity of propolis [PDF]
Redox Report, 2002 We investigated the radical scavenging activity of propolis by ESR spectroscopy using spin trapping method. In addition, we examined the influence of a diet of 2% propolis on mice under oxidative stress. At low concentrations, the methanolic extract of propolis exhibited strong scavenging activity in vitro towards both the superoxide anion radical ...
Kazutoyo Endo +7 more
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Free radical scavenging properties of pyrimidine derivatives [PDF]
Organic and Medicinal Chemistry Letters, 2012 Free radicals are well known for playing a dual role in our body- deleterious as well as beneficial. It includes a metabolic pathway for its generation. Oxidative stress in our body occurs due to excessive generation of free radicals and reduced level of antioxidants, but at low concentrations, these radicals help to perform normal physiological ...
Rupesh Dudhe, Tabassum Bano, Nitin Kumar
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Multiple free-radical scavenging capacity in serum [PDF]
Journal of Clinical Biochemistry and Nutrition, 2012 We have developed a method to determine serum scavenging-capacity profile against multiple free radical species, namely hydroxyl radical, superoxide radical, alkoxyl radical, alkylperoxyl radical, alkyl radical, and singlet oxygen. This method was applied to a cohort of chronic kidney disease patients.
Masashi Shimmei +4 more
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Free Radical Scavenging Activity of Elsholtzia densa
Journal of Acupuncture and Meridian Studies, 2012 Medicinal plants have been used traditionally to cure a variety of diseases since ancient times. Elsholtzia densa, a rare annual herb of the Kashmir valley, was assessed for its antioxidant efficacy. Antioxidant activity of the crude extracts was evaluated using 1, 1- diphenyl-2-picryl hydrazyl free radical (DPPH), DNA sugar damage, lipid peroxidation,
Akbar Masood +7 more
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Dual aspect of radioenhancers and free radical scavengers
Free Radical Biology and Medicine, 2020 Combining an external beam of ionizing particles with agents to augment the dose effects of cell damages for therapeutic purpose is an important goal of radiotherapy. This last decade intensive works have focused on metal compounds or metal nanoparticles as radiosensitizers to increase the oxidative damages under irradiation.
Claude Le Sech, Ryoichi Hirayama
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Skin health properties of Paeonia lactiflora flower extracts and tyrosinase inhibitors and free radical scavengers identified by HPLC post-column bioactivity assays. [PDF]
Heliyon, 2023 Zhou H, Li T, Li B, Sun S.
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Free radical scavenging activity v1 [PDF]
, 2018 Free radical scavenging assay was measured using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical test. To each aqueous extract 3 mL of 0.1 mM solution of DPPH in methanol was added (Fermont, Monterrey). Tubes were shaken vigorously and allowed to stand for 30 min at room temperature in the dark. Absorbance was measured at 517 nm.
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