Results 41 to 50 of about 29,947 (258)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Simple isatin derivatives as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship

open access: yesChemistry Central Journal, 2011
To develop more potent small molecules with enhanced free radical scavenger properties, a series of N-substituted isatin derivatives was synthesized, and the cytoprotective effect on the apoptosis of PC12 cells induced by H2O2 was screened.
Mu Shuzhen   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The Promising Free Radical Scavenging Activity of Some Fabaceae Flowers

open access: yesMajalah Obat Tradisional
Oxidative stress caused by free radicals is a key contributor to the development of chronic diseases. As a natural defense strategy, the identification of plant-based free radical scavengers has become increasingly important.
Esa Agung Nurrohmat   +2 more
doaj   +1 more source

Correlation of serum IgE with stress in Indian dromedaries affected with skin wounds [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2010
The present investigation was planned to explore stress induced changes in the levels of IgE by correlating them with the important parameters of stress like cortisol and free radical scavengers in the serum of Indian dromedaries.
A.K Kataria, N. Kataria, R. Maan
doaj  

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

open access: yesAdvanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni   +7 more
wiley   +1 more source

Formulation and Characterisation of a Hydrogel Infused with Scutellaria baicalensis Root Extract and Zinc Oxide Nanoparticles: An In-vitro Evaluation of Antioxidant, Anti-inflammatory, and Cytotoxic Effects [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Scutellaria baicalensis, rich in bioactive flavonoids such as baicalin and baicalein, exhibits potent antioxidant, anti-inflammatory, and antimicrobial activities.
A Mohamed Thaha, Arvina Rajasekar
doaj   +1 more source

Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions

open access: yesAdvanced Functional Materials, EarlyView.
This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian   +7 more
wiley   +1 more source

Achieving High ON State Current through Ferroelectric Polarization‐Dependent Interfacial Resistance Switching in Undoped Orthorhombic HfO2 Films

open access: yesAdvanced Functional Materials, EarlyView.
Ferroelectric tunnel junction devices based on epitaxial undoped ferroelectric HfO2 films demonstrate stable switching endurance of over 106 switching cycles, low write voltages of ±3 V, 16 measured resistance states, and neuromorphic capability.
Markus Hellenbrand   +13 more
wiley   +1 more source

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