Free radical scavengers in anaesthesiology and critical care. [PDF]
Indian J Anaesth, 2012 Free radicals are highly reactive and unstable compounds. These highly reactive molecules cause oxidative damage to cellular components such as DNA, proteins and lipids. They play central role in the mechanism of cell injury and cell death. Free radical scavengers either prevent these reactive species from being formed, or remove them before they can ...
Hatwalne MS.
europepmc +5 more sources
Captopril: a free radical scavenger. [PDF]
British Journal of Clinical Pharmacology, 1989 The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopril is a free radical scavenger and we suggest that
Chopra, M. +6 more
openaire +4 more sources
Why Ortho- and Para-Hydroxy Metabolites Can Scavenge Free Radicals that the Parent Atorvastatin Cannot? Important Pharmacologic Insight from Quantum Chemistry [PDF]
Molecules, 27 (15), 5036 (2022), 2022 The pharmaceutical success of atorvastatin (ATV), a widely employed drug against the "bad" cholesterol (LDL) and cardiovascular diseases, traces back to its ability to scavenge free radicals. Unfortunately, information on its antioxidant properties is missing or unreliable.
arxiv +1 more source
Scavenging Effects of Dexrazoxane on Free Radicals [PDF]
Journal of Clinical Biochemistry and Nutrition, 2010 Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation ...
Zhao Yan, Zhao Baolu, Zhang Junjing
openaire +3 more sources
Free radical scavenging activity of propolis [PDF]
Redox Report, 2002 We investigated the radical scavenging activity of propolis by ESR spectroscopy using spin trapping method. In addition, we examined the influence of a diet of 2% propolis on mice under oxidative stress. At low concentrations, the methanolic extract of propolis exhibited strong scavenging activity in vitro towards both the superoxide anion radical ...
Kazutoyo Endo +7 more
openaire +2 more sources
Radical triads, not pairs, may explain effects of hypomagnetic fields on neurogenesis [PDF]
, 2022 Adult hippocampal neurogenesis and hippocampus-dependent cognition in mice have been found to be adversely affected by hypomagnetic field exposure. The effect concurred with a reduction of reactive oxygen species in the absence of the geomagnetic field.
arxiv +1 more source
Functionalization of graphene sponge electrodes with two-dimensional materials for tailored electrocatalytic activity towards specific contaminants of emerging concern [PDF]
Chemical Engineering Journal, 2022, 2022 Low-cost graphene sponge electrodes were functionalized with two-dimensional (2D) materials, i.e., borophene and hexagonal boron nitride (hBN), using a one-step, hydrothermal self-assembly method. Borophene and hBN-modified graphene sponge anode and N-doped graphene sponge cathode were employed for electrochemical degradation of model persistent ...
arxiv +1 more source
1,1-Diphenyl-2-picrylhydrazyl and superoxide anion radical scavenging 1 activities of heterocyclic 2-oxo-1,2,3,4-tetrahydropyrimidines [PDF]
arXiv, 2023 To investigate1,1-Diphenyl-2-picrylhydrazyl (DPPH) and superoxide radical (SOR) 17 scavenging activities of 2-oxo-1,2,3,4-tetrahydropyrimidines derivatives. Free radicals are 18 highly unstable and reactive molecules/atoms. In the body, free radicals form during 19 normal and abnormal metabolism in the body and cause serious damage to other 20 ...
arxiv
Estimation of In-Vitro Free Radical Scavenging and Cytotoxic Activities of Thiocarbohydrazones Derivatives [PDF]
arXiv, 2023 Objective: To investigate free radical scavenging potential of thiocarbohydrazones derivatives for the discovery of antioxidant compounds of synthetic origin. Method: Eighteen thiocarbohydrazones derivatives were screened for antioxidant activities by using in vitro radical inhibition assay.
arxiv
Free radical scavenging properties of pyrimidine derivatives [PDF]
Organic and Medicinal Chemistry Letters, 2012 Free radicals are well known for playing a dual role in our body- deleterious as well as beneficial. It includes a metabolic pathway for its generation. Oxidative stress in our body occurs due to excessive generation of free radicals and reduced level of antioxidants, but at low concentrations, these radicals help to perform normal physiological ...
Rupesh Dudhe, Tabassum Bano, Nitin Kumar
openaire +3 more sources