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Multiple free radical scavenging reactions of aurones
Phytochemistry, 2021A series of naturally occurring 3',4'-dihydroxy aurones have been studied with regard to multiple free radical scavenging reactions in the gas and two liquid phases using density functional theory (DFT). All of the aurones prefer to perform (2 + n)-HAT mechanism to trap 2 + n free radicals, where n is the sum of the numbers of catechol and guaiacyl ...
Zheng, Yan-Zhen +2 more
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Free Radical Scavenging Action of Baicalein
Archives of Biochemistry and Biophysics, 1993TJ-960 is a Japanese Kampo (traditional herbal) medicine used for the treatment of epilepsy. It's a crude drug, an extract of nine herbs, and consists of many known and unknown components. Among the known components of TJ-960, we found that 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one (baicalein) might be the most potent scavenger for radicals.
H, Hamada +3 more
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The Significance of Free Radicals and Free Radical Scavengers in L1210 Leukemia
1988L1210 leukemia is a murine leukemia which is associated with anemia and marked neutrophilia. In order to determine the significance of free radicals (FR) in this disorder, we determined the presence and localization of free radical scavengers (FRS) and scavenger-like systems in L1210 leukemia cells obtained in vivo and from in vitro cultures.
A C, Brown, J D, Lutton
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Carnitine as a free radical scavenger in aging
Experimental Gerontology, 2001Carnitine (4-N-trimethylammonium-3-hydroxybutyric acid) plays an important role in the translocation of acetyl moieties from the mitochondria into the cytoplasm for acetylcholine synthesis in the brain. Previous studies in our laboratory have shown that L-carnitine suppresses oxidative damage during aging.
P J, Arockia Rani, C, Panneerselvam
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The anticonvulsant zonisamide scavenges free radicals
Epilepsy Research, 1998Zonisamide (ZNS) is effective in animal models of epilepsy and epileptic patients. The free radical scavenging activities of ZNS were analyzed by using electron spin resonance. ZNS, in the mmolar range, scavenged hydroxyl and nitric oxide radicals in a dose-dependent manner.
A, Mori, Y, Noda, L, Packer
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Copper or free radical scavenger?
Computational and Theoretical Chemistry, 2017Abstract Free radicals are very reactive molecules that produce so-called oxidative stress. To prevent oxidative stress there are two types of molecules: primary and secondary antioxidants. The chelation of copper is an example of a secondary antioxidant process. Therefore, these secondary antioxidants can be named copper scavengers. The main purpose
Ana Martínez, Miguel Reina
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Free radical scavenging Activity :
DIU Journal of Health and Life Sciences, 2014The present study was aimed at investigating the chemical profiles of the methanolic extract of leaves of Centella asiatica as well as to assess its antioxidative activity. In this study, a methanolic extract (50 g/L) was obtained by infusion followed by cold maceration for 24 h.
Md. Mustafezur Rahman +4 more
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Studies on the activity of bepridil as a scavenger of free radicals
Biochemical Pharmacology, 1990Bepridil, a calcium antagonist with anti-anginal, anti-ischemic, and anti-arrhythmic properties was assessed for its ability to scavenge free radicals. Bepridil reduced the stable free radical 1,1-diphenyl-2-picrylhydrazil (DPPH) in the molar ratio 2:1 and, in this respect, was as active as the reference anti-oxidants hydroquinone and alpha-tocopherol.
M, Constantin +3 more
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Free Radical Scavenging Activity of Papaya Juice
International Journal of Radiation Biology, 1989Papaya juice is an efficient scavenger of highly reactive hydroxyl radicals (OH.) formed during 60Co irradiation of water. The OH. radicals were detected by the electron spin resonance (ESR) technique of spin trapping using DMPO (5,5-dimethyl-1-pyrroline-N-oxide) or by a colorimetric assay in which salicylate is converted into polyhydroxybenzoic acids.
E J, Webman, G, Edlin, H F, Mower
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Free Radical Scavenging by Ethanol Extract of Propolis
International Journal of Radiation Biology, 1990The free radical scavenging ability of an ethanolic extract of propolis (EEP) was demonstrated by electron spin resonance spectroscopy, when 2,2-diphenyl-1-picrylhydrazyl (DPPH) was treated with increasing concentrations of EEP. It was shown that the DPPH signal intensity was inversely related to the EEP concentration and to the reaction time.
S, Scheller +5 more
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