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Free Radical Scavenging Properties of Sulfinpyrazone
Free Radical Research, 2002Sulfinpyrazone, a potent uricosuric drug, was tested in vitro for its scavenging action against oxygen free radicals. In this study, sulfinpyrazone was able to scavenge 1,1-diphenyl-2-picrylhydrazyl radical with IC50 value of 29.82 micrograms/ml compared to butylated hydroxytoluene (BHT, IC50 value = 20.15 micrograms/ml) and Trolox (IC50 value = 16.01 ...
Mei-Ling, Yang +3 more
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Carnitine as a free radical scavenger in aging
Experimental Gerontology, 2001Carnitine (4-N-trimethylammonium-3-hydroxybutyric acid) plays an important role in the translocation of acetyl moieties from the mitochondria into the cytoplasm for acetylcholine synthesis in the brain. Previous studies in our laboratory have shown that L-carnitine suppresses oxidative damage during aging.
P J, Arockia Rani, C, Panneerselvam
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The Significance of Free Radicals and Free Radical Scavengers in L1210 Leukemia
1988L1210 leukemia is a murine leukemia which is associated with anemia and marked neutrophilia. In order to determine the significance of free radicals (FR) in this disorder, we determined the presence and localization of free radical scavengers (FRS) and scavenger-like systems in L1210 leukemia cells obtained in vivo and from in vitro cultures.
A C, Brown, J D, Lutton
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Free Radical Scavenging Action of Baicalein
Archives of Biochemistry and Biophysics, 1993TJ-960 is a Japanese Kampo (traditional herbal) medicine used for the treatment of epilepsy. It's a crude drug, an extract of nine herbs, and consists of many known and unknown components. Among the known components of TJ-960, we found that 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one (baicalein) might be the most potent scavenger for radicals.
H, Hamada +3 more
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The anticonvulsant zonisamide scavenges free radicals
Epilepsy Research, 1998Zonisamide (ZNS) is effective in animal models of epilepsy and epileptic patients. The free radical scavenging activities of ZNS were analyzed by using electron spin resonance. ZNS, in the mmolar range, scavenged hydroxyl and nitric oxide radicals in a dose-dependent manner.
A, Mori, Y, Noda, L, Packer
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Copper or free radical scavenger?
Computational and Theoretical Chemistry, 2017Abstract Free radicals are very reactive molecules that produce so-called oxidative stress. To prevent oxidative stress there are two types of molecules: primary and secondary antioxidants. The chelation of copper is an example of a secondary antioxidant process. Therefore, these secondary antioxidants can be named copper scavengers. The main purpose
Ana MartÃnez, Miguel Reina
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Free radical scavenging Activity :
DIU Journal of Health and Life Sciences, 2014The present study was aimed at investigating the chemical profiles of the methanolic extract of leaves of Centella asiatica as well as to assess its antioxidative activity. In this study, a methanolic extract (50 g/L) was obtained by infusion followed by cold maceration for 24 h.
Md. Mustafezur Rahman +4 more
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Probucol, a superoxide free radical scavenger in vitro
Atherosclerosis, 1991Free radical (FR) mediated oxidation of low density lipoproteins (LDL) has been implicated in atherogenesis. Probucol is a lipid lowering agent with antioxidant properties which may protect the LDL from FR mediated damage. The specific mechanism by which probucol acts as an antioxidant has not previously been reported.
Bridges, A.B. +2 more
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1994
Free radical chemistry is characterized by an unregulated chain reaction of sequential oxidations and reductions that can rapidly amplify the concentration of reactive radicals. The free radical is defined by the occurrence of an unpaired electron in an organic molecule or metal ion (Halliwell & Gutteridge, 1989).
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Free radical chemistry is characterized by an unregulated chain reaction of sequential oxidations and reductions that can rapidly amplify the concentration of reactive radicals. The free radical is defined by the occurrence of an unpaired electron in an organic molecule or metal ion (Halliwell & Gutteridge, 1989).
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Free Radical Scavenging Activity of Papaya Juice
International Journal of Radiation Biology, 1989Papaya juice is an efficient scavenger of highly reactive hydroxyl radicals (OH.) formed during 60Co irradiation of water. The OH. radicals were detected by the electron spin resonance (ESR) technique of spin trapping using DMPO (5,5-dimethyl-1-pyrroline-N-oxide) or by a colorimetric assay in which salicylate is converted into polyhydroxybenzoic acids.
E J, Webman, G, Edlin, H F, Mower
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