Benzophenone Semicarbazones as Potential alpha-glucosidase and Prolyl Endopeptidase Inhibitor: In-vitro free radical scavenging, enzyme inhibition, mechanistic, and molecular docking studies [PDF]
arXiv, 2023 $\alpha$-glucosidase and prolylendopeptidase has altered expression and activity patterns in neurological disease, type 2diabetes respectively and several cancers. Here we screened a series 1-29 benzophenone semicarbazone derivatives for in vitro free radical scavenging, alpha-glucosidase and prolylendopeptidase inhibition activities. Seven derivatives
arxiv
Photocatalytic Behavior of Fluorinated Rutile TiO$_2$(110) Surface: Understanding from the Band Model [PDF]
Solar RRL 1, 1700183 (2017), 2017 Surface fluorination of TiO$_2$ (F-TiO$_2$) has complicate photocatalytic behavior in degradation of organic compounds. This work attempts to establish an elegant scenario based on the band model to understand this behavior. Density functional theory (DFT) calculations show that fluorination of the rutile TiO$_2$(110) surface (F-TiO$_2$${110}$) results
arxiv +1 more source
Highly Catalytic Nanodots with Renal Clearance for Radiation Protection [PDF]
ACS Nano 2016, 2016 Ionizing radiation (gamma and x-ray) is widely used in industry and medicine, but it can also pose a significant hazardous effect on health and induce cancer, physical deformity and even death, due to DNA damages and invasion of free radicals. There is therefore an urgent unmet demand in designing highly efficient radioprotectants with synergetic ...
arxiv +1 more source
Multiple free-radical scavenging capacity in serum [PDF]
Journal of Clinical Biochemistry and Nutrition, 2012 We have developed a method to determine serum scavenging-capacity profile against multiple free radical species, namely hydroxyl radical, superoxide radical, alkoxyl radical, alkylperoxyl radical, alkyl radical, and singlet oxygen. This method was applied to a cohort of chronic kidney disease patients.
Masashi Shimmei +4 more
openaire +3 more sources
Dual aspect of radioenhancers and free radical scavengers
Free Radical Biology and Medicine, 2020 Combining an external beam of ionizing particles with agents to augment the dose effects of cell damages for therapeutic purpose is an important goal of radiotherapy. This last decade intensive works have focused on metal compounds or metal nanoparticles as radiosensitizers to increase the oxidative damages under irradiation.
Le Sech, Claude, Hirayama, Ryoichi
openaire +5 more sources
The sensitivity of a radical pair compass magnetoreceptor can be significantly amplified by radical scavengers [PDF]
Scientific Reports 7, Article number: 11640 (2017), 2017 Birds have a remarkable ability to obtain navigational information from the Earth's magnetic field. The primary detection mechanism of this compass sense is uncertain but appears to involve the quantum spin dynamics of radical pairs formed transiently in cryptochrome proteins.
arxiv +1 more source
Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]
arXiv, 2020 A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv
Free Radical Scavenging Activity of Elsholtzia densa
Journal of Acupuncture and Meridian Studies, 2012 Medicinal plants have been used traditionally to cure a variety of diseases since ancient times. Elsholtzia densa, a rare annual herb of the Kashmir valley, was assessed for its antioxidant efficacy. Antioxidant activity of the crude extracts was evaluated using 1, 1- diphenyl-2-picryl hydrazyl free radical (DPPH), DNA sugar damage, lipid peroxidation,
Akbar Masood +7 more
openaire +3 more sources
Scavengers in the human-dominated landscape: an experimental study [PDF]
arXiv, 2022 Rapid urbanization is a major cause of habitat and biodiversity loss and human-animal conflict. While urbanization is inevitable, we need to develop a good understanding of the urban ecosystem and the urban-adapted species in order to ensure sustainable cities for our future. Scavengers play a major role in urban ecosystems, and often, urban adaptation
arxiv
Effect of intense, ultrashort laser pulses on DNA plasmids in their native state: strand breakages induced by {\it in-situ} electrons and radicals [PDF]
Phys. Rev. Letters 106 (2011) 118101, 2011 Single strand breaks are induced in DNA plasmids, pBR322 and pUC19, in aqueous media exposed to strong fields generated using ultrashort laser pulses (820 nm wavelength, 45 fs pulse duration, 1 kHz repetition rate) at intensities of 1-12 TW cm$^{-2}$.
arxiv +1 more source