Results 161 to 170 of about 3,933,717 (303)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Editorial: Fruit Ripening: From Present Knowledge to Future Development

Frontiers in Plant Science, 2019
José M. Palma, Francisco J. Corpas, Luciano Freschi, Victoriano Valpuesta   +3 more
doaj   +1 more source

Correction: Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors. [PDF]

Chem Sci
Piris P, Buric D, Yamasaki T, Huchedé P, Rossi M, Matteudi M, Montero MP, Rodallec A, Appay R, Roux C, Combes S, Pasquier E, Castets M, André N, Brémond P, Carré M.   +15 more
europepmc   +1 more source

Free radicals and oxidation phenomena in biological systems

, 1995
This concise reference offers an incomparable analysis of the biological processes mediated by free radicals from a toxicological point of view - explaining in detail the chemistry and biochemistry of all principal types of radicals and providing easy ...
Roberfroid, Marcel B., Buc Calderon, Pedro   +1 more
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Associations between Environmental Persistent Free Radicals, Reactive Oxygen Species, and Oxidative Potential in Atmospheric Aerosols. [PDF]

ACS Omega
Wang S, Guo Y, Wei F, Guo H, Huang S.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Expression and Roles of Free Radicals and Reactive Oxygen Species in Hearing Loss. [PDF]

Antioxidants (Basel)
Lee JM, Cha YJ, Oh YJ, Kim HO, Kim SS, Kim YJ, Yon DK, Yeo SG.   +7 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Exposure of Selected Sunscreens to Artificial Sunlight Generates Persistent Free Radicals. [PDF]

Environ Sci Technol Lett
Vejerano EP, Khushboo K, Vejerano J, Ballejipalli SK.   +3 more
europepmc   +1 more source