Results 181 to 190 of about 5,663,581 (403)

Studies on the Free Radical in Amino-Carbonyl Reaction

open access: bronze, 1965
Hisateru Mitsuda   +2 more
openalex   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Environmentally Persistent Free Radicals: Insights on a New Class of Pollutants.

open access: yesEnvironmental Science and Technology, 2018
Eric P. Vejerano   +4 more
semanticscholar   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Studies on free radicals, antioxidants, and co-factors

open access: yesClinical Interventions in Aging, 2007
Khalid RahmanSchool of Biomolecular Sciences, Liverpool John Moores University, Liverpool, England, UKAbstract: The interplay between free radicals, antioxidants, and co-factors is important in maintaining health, aging and age-related diseases.
Khalid Rahman
doaj  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Leaves are a Source of Biogenic Persistent Free Radicals. [PDF]

open access: yesEnviron Sci Technol Lett, 2023
Vejerano EP, Ahn J.
europepmc   +1 more source

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