Results 191 to 200 of about 3,754,131 (296)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Free radicals and cardiac anaesthesia

Indian Journal of Anaesthesia, 2013
Samarjit Bisoyi, Jitendu Mohanty
doaj   +1 more source

Quantitative Suspension Test for the Evaluation of a Cold Sterilization System Based on Reducing Free Radicals Compared to Autoclave Sterilization Cycles. [PDF]

J Funct Biomater
Cirillo C, Botticelli D, Benedicenti S.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Reactive oxygen species as mediators of the activation of glucose transport in M07e cells: role of intracellular calcium

, 2004
LANDI, LAURA, PRATA, CECILIA, Maraldi T., FIORENTINI, DIANA, HAKIM, GABRIELE   +4 more
core   +1 more source

Electron paramagnetic resonance spectroscopy for analysis of free radicals in zebrafish. [PDF]

PLoS One
Sabetghadam Moghadam M, Wiens E, Gauvrit S, Sammynaiken R, Collins MM.   +4 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Quantum sensing of free radicals in macrophages reveals early autophagy-lysosome regulation in an atherosclerosis cell model. [PDF]

Redox Biol
Fan S, Gao H, Nieuwhof W, Mulder T, Fumelli BFM, Li R, Sharmin R, Niora M, Machado-Santelli GM, Berg Sorensen K, de Haan W, Santos HA, Schirhagl R.   +12 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Multifunctional Activity of Syzygium aromaticum Extracts Against Candida albicans: Free Radicals, Membrane Permeabilization and Cdr1p Localization. [PDF]

Int J Mol Sci
Derkacz D, Cebula L, Krasowska A.
europepmc   +1 more source