Results 221 to 230 of about 320,731 (312)

Retraction Note: Carbon dot nanozymes as free radicals scavengers for the management of hepatic ischemia-reperfusion injury by regulating the liver inflammatory network and inhibiting apoptosis. [PDF]

J Nanobiotechnology
Geng H, Chen J, Tu K, Tuo H, Wu Q, Guo J, Zhu Q, Zhang Z, Zhang Y, Huang D, Zhang M, Xu Q.   +11 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Detecting Mitochondrial Free Radicals with Quantum Sensors: From Organelles to a D. melanogaster Model of Neurodegeneration

Menon S, Reed J, Ebanks B, Shanmugham M, Brookfield A, Collison D, Sow M, James V, Mongan NP, Moisoi N, Jelezko F, Chakrabarti L, Mather ML.   +12 more
europepmc   +1 more source

Quantification of Total Free Radicals in <i>Drosophila</i> Using a Fluorescence-Based Biochemical Assay. [PDF]

Bio Protoc
Arzoo SH, Tasmin R, Banerjee SJ.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Associations between household characteristics and environmentally persistent free radicals in house dust from two Australian locations. [PDF]

Front Public Health
Lee WR, Dangal P, Langan G, Lazarevic N, Xu Z, Cormier SA, Lomnicki S, Sly PD, Vilcins D.   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Plasma membrane electron transport (tPMET) in two human megakaryocytic cell lines.

, 2004
LANDI, LAURA, PRATA, CECILIA, Maraldi T., FIORENTINI, DIANA, ZAMBONIN, LAURA, HAKIM, GABRIELE   +5 more
core  

Oxidative potential and persistent free radicals in dust storm particles and their associations with hospitalization. [PDF]

Nat Commun
Qin L, Yang L, Liu L, Tong S, Liu Q, Li G, Zhang H, Zhu W, Liu G, Zheng M, Jiang G.   +10 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source