Results 101 to 110 of about 9,437,217 (301)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Free Surface Analysis of Spillway Flow under Radial Gate by EFG-NE Method [PDF]

open access: yesمهندسی منابع آب, 2017
The element-free Galerkin method (EFG) and the natural element method (NEM) are two well know methods in the computational mechanics and meshless methods. In this paper, a computational scheme using a variable domain and a fixed domain is presented based
Seyyed Abdossamad Javanmard
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Transient free surface flow past a two-dimensional flat stern

open access: yes, 2015
A transient free surface flow past a two-dimensional semi-infinite flat plate in the fluid of a finite depth is considered in the linear approximation. It is assumed that the fluid is inviscid and incompressible and the flow is irrotational. The plate is
Stepanyants, Yury, Ogilat, Osama
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Free convection boundary layers driven by exothermic surface reactions: critical ambient temperatures [PDF]

open access: yes, 1995
A model for the free convection boundary-layer flow near a forward stagnation point driven by heating from a surface on which there is a catalytic reaction is discussed.
Liñán Martínez, Amable   +2 more
core  

Some modifications of MPS method for incompressible free surface flow

open access: yes
As a Lagrangian mesh-free method, the Moving Particle Semi-implicit (MPS)[1] method is very suitable for simulating violent flows, such as breaking waves on free surface.
Xing, J.T.   +3 more
core   +1 more source

Flow past a sphere at the free-surface using URANS

open access: yes, 2013
The flow past a sphere located at the free-surface, was studied over the critical Reynolds number range: 2x10^5 to 4x10^5. Experiments were carried out in the Lamont tank at the University of Southampton.
Hudson, D.A., James, M., Turnock, S.R.
core   +1 more source

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