Results 101 to 110 of about 989,743 (383)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Effects of Thawing Temperature of Frozen rare Breed Hanwoo (Korean Native Cattle) Semen on Viability of Refrozen Spermatozoa

Journal of Animal Reproduction and Biotechnology, 2017
Cryopreservation of germ cells from genetically proven animals could be a source of restoration tools from the risk of extinction or disappearance of wanted characteristics.
Min Su Kim, Arum Choi, Chan-Lan Kim, Dongkyo Kim, Hwan-Hoo Seong, Sung Woo Kim   +5 more
doaj   +1 more source

Transverse Ising Chain under Periodic Instantaneous Quenches: Dynamical Many-Body Freezing and Emergence of Solitary Oscillation

, 2012
We study the real-time dynamics of a quantum Ising chain driven periodically by instantaneous quenches of the transverse field (the transverse field varying as rectangular wave symmetric about zero).
Bhattacharyya, Sirshendu, Das, Arnab, Dasgupta, Subinay   +2 more
core   +1 more source

Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods [PDF]

, 2014
In the preservation of tissues in as ‘close to life’ state as possible, rapid freeze fixation has many benefits over conventional chemical fixation. One technique by which rapid freeze-fixation can be achieved, high pressure freezing (HPF), has been ...
A. Bullen, A. Forge, Al-Amoudi, B. Kachar, Boyde, C. Moores, Caulfield, Claeys, Dahl, Derosier, Dubochet, Dumont, Flock, Forge, Galway, Gilkey, Hayat, Hirokawa, Kachar, Kachar, Kellenberger, Koster, Leforestier, Lucic, McDonald, McDonald, Meissner, Meyer, Muller, Ohta, R.A. Fleck, R.R. Taylor, Resch, Rzadzinska, Schneider, Semmler, Small, Small, Sosinsky, Sosinsky, Steinbrecht, Studer, Studer, Studer, Studer, Taylor, Tilney, White   +47 more
core   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Restartable heat pipe [PDF]

, 1972
Inclusion in heat pipe of auxiliary working fluid which has considerably lower freezing point than main working fluid enables easy starting after main working fluid has been cooled to or below freezing ...
Shlosinger, A. P.
core   +1 more source

Effect of local filtering on Freezing Phenomena of Quantum Correlation

, 2015
General quantum correlations measures like quantum discord, one norm geometric quantum discord, exhibit freezing, sudden change, double sudden change behavior in their decay rates under different noisy channels.
Bhar, Amit, Karmakar, Sumana, Sarkar, Debasis, Sen, Ajoy   +3 more
core   +1 more source

Olfactory inputs modulate respiration-related rhythmic activity in the prefrontal cortex and freezing behavior

Nature Communications, 2018
Respiration and airflow through the nasal cavity are known to be correlated with rhythmic neural activity in the central nervous system. Here we show in rodents that during conditioned fear-induced freezing behavior, mice breathe at a steady rate (~4 Hz),
A. Moberly, M. Schreck, J. Bhattarai, L. Zweifel, Wenqin Luo, M. Ma   +5 more
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Freezing in random graph ferromagnets

, 2001
Using T=0 Monte Carlo and simulated annealing simulation, we study the energy relaxation of ferromagnetic Ising and Potts models on random graphs. In addition to the expected exponential decay to a zero energy ground state, a range of connectivities for ...
A.J. Bray, B. Bollobás, C.H. Papadimitriou, D.A. Johnston, N. Metropolis, N.R. da Silva, P. Svenson, Pontus Svenson, R. Mélin, R.J. Glauber, S. Kirkpatrick   +10 more
core   +1 more source