Results 191 to 200 of about 989,743 (383)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

The Relation of the Thyroid to Autolysis, with a Preliminary Report on the Study of Autolysis by Determinations of the Changes in Freezing Point and Electrical Conductivity

, 1907
H. Gideon Wells, Robert L. Benson
openalex   +1 more source

On the Second Differential Coefficients of Gibbs’ Function ζ. The Vapour Tensions, Freezing and Boiling Points of Ternary Mixtures [PDF]

, 1897
Walter L. Miller
openalex   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

On the Molecular Depression of the Freezing-point of Water Produced by Some Very Concentrated Saline Solutions [PDF]

, 1904
L. C. de Coppet
openalex   +1 more source

A Perspective on Powder Metallurgy and Additive Manufacturing of High‐Nitrogen Alloyed Stainless Steels

Advanced Engineering Materials, EarlyView.
This perspective article explores an innovative powder metallurgical approach to producing high‐nitrogen steels by utilizing a mixture of stainless steel and Si3N4. This mixture undergoes hot isostatic pressing followed by direct quenching. The article also examines adapting this method to laser powder bed fusion (PBF‐LB/M) to overcome nitrogen ...
Louis Becker, Felix Radtke, Jonathan Lentz, Simone Herzog, Christoph Broeckmann, Sebastian Weber   +5 more
wiley   +1 more source

The freezing temperatures of some fruits, vegetables, and cut flowers /

, 1923
R. C. Wright, G. Flint Taylor
openalex   +2 more sources

PRESERVATION OF STOCK CULTURES OF BACTERIA BY FREEZING AND DRYING [PDF]

, 1921
Homer F. Swift
openalex   +1 more source

A Novel Approach on Rapid Alloy Development of Tool Steels for Laser Powder Bed Fusion by In Situ Alloying

Advanced Engineering Materials, EarlyView.
A novel approach for alloy development in laser powder bed fusion is introduced. Instead of producing massive samples of one composition at a time, prepressed powder bed samples produced from powder mixtures are processed. Guidelines for the selection of precursor powders are developed.
Felix Großwendt, Anna Strauch, Jonathan Lentz, Arne Röttger, Rainer Fechte‐Heinen, Sebastian Weber, Werner Theisen   +6 more
wiley   +1 more source