Results 151 to 160 of about 2,131 (185)
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Fremanezumab for the prevention of chronic and episodic migraine
Drugs of Today, 2019On September 15, 2018, the U.S. Food and Drug Administration (FDA) approved subcutaneous fremanezumab, a calcitonin gene-related peptide (CGRP) monoclonal antibody, for the treatment of episodic and chronic migraine in adults, with two recommended dosages: 225 mg monthly or 675 mg every 3 months.
L, Lionetto +3 more
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Fremanezumab in Children and Adolescents with Episodic Migraine
New England Journal of MedicineFremanezumab, a humanized monoclonal antibody that selectively targets calcitonin gene-related peptide, is approved for the prevention of migraine in adults. Evidence from randomized, controlled trials in children and adolescents is needed.We randomly assigned participants 6 to 17 years of age with a diagnosis of episodic migraine (defined as migraine ...
Andrew D, Hershey +10 more
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Fremanezumab: Pediatric First Approval
Pediatric DrugsFremanezumab (fremanezumab-vfrm; AJOVY®) is a humanized monoclonal antibody developed by Teva Pharmaceuticals to selectively target calcitonin gene-related peptide (a vasodilatory neuropeptide involved in the pathophysiology of migraine). Fremanezumab was first approved in September 2018 in the USA for the prevention of migraine in adults.
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Fremanezumab-associated injection site alopecia
BMJ Case ReportsCalcitonin gene-related peptide (CGRP) inhibitors, in the form of injectable monoclonal antibodies, are a newer class of drugs for the prevention of migraine headaches. In clinical trials, they have been found to be effective with good tolerance and few adverse effects. Alopecia has been increasingly noted as a post-marketing event associated with CGRP
Mark, Esguerra, Emily Rubenstein, Engel
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Fremanezumab as a preventive treatment for episodic and chronic migraine
Expert Review of Neurotherapeutics, 2019Introduction: The importance of calcitonin gene-related peptide (CGRP) in migraine pathogenesis is well established. Fremanezumab is a humanized IgG2a monoclonal antibody that binds to CGRP. Areas covered: In this paper, we review the development of fremanezumab, from early development into approval.
Marcelo E, Bigal +2 more
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Hypersensitivity to galcanezumab with tolerance to erenumab and fremanezumab
The Journal of Allergy and Clinical Immunology: In Practice, 2023Beatriz, González-Cano +5 more
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