Results 101 to 110 of about 2,177,340 (291)

Numerical solution of Rayleigh-Lamb frequency equation for real, imaginary and complex wavenumbers

MATEC Web of Conferences, 2018
Guided waves, especially Lamb waves or shear-horizontal waves, are widely used types of waves for ultrasonic inspection of large structures. Well known property of guided waves is their dispersive character, which means that the propagation velocity of ...
Šofer Michal, Ferfecki Petr, Šofer Pavel   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Estimate of intense rainfall equation parameters for rainfall stations of the Paraíba State, Brazil

Pesquisa Agropecuária Tropical, 2017
Rainfall is the primary water source for hydrographic basins. Hence, the quantification and knowledge of its temporal and spatial distribution are indispensable in dimensioning hydraulic projects.
Alcinei Ribeiro Campos, João Batista Lopes da Silva, Glenio Guimarães Santos, Rafael Felippe Ratke, Itauane Oliveira de Aquino   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Synchronization of Two Non-Identical Coupled Exciters in a Non-Resonant Vibrating System of Linear Motion. Part I: Theoretical Analysis

Shock and Vibration, 2009
In this paper an analytical approach is proposed to study the feature of frequency capture of two non-identical coupled exciters in a non-resonant vibrating system.
Chunyu Zhao, Hongtao Zhu, Ruizi Wang, Bangchun Wen   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Analysis of the Main Factors Influencing the Dominant Frequency of Blast Vibration

Shock and Vibration, 2019
At present, the study on the dominant frequency of blasting vibration is still a worldwide problem. Compared with the mature research on the particle peak velocity of blasting vibration, the researches on the dominant frequency of blasting vibration are ...
Da Liu, Wenbo Lu, Yijia Liu, Ming Chen, Peng Yan, Pengchang Sun   +5 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Exact solution of the differential equation of transverse oscillations of the rod taking into account own weight

MATEC Web of Conferences, 2017
The free transverse oscillations of the rod of uniform cross section taking into account its own weight are considered in this work. The appropriate partial differential equation of transverse oscillations of a rod was reduced to two ordinary ...
Krutii Yurii, Suriyaninov Mykola, Vandynskyi Victor   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source