Results 121 to 130 of about 2,195,899 (341)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
High-frequency propagation for the Schrödinger equation on the torus
18 ...
openaire +4 more sources
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Flare Frequency Distributions Based on a Master Equation [PDF]
M. S. Wheatland, S. Glukhov
openalex +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Symmetries and invariants of the oscillator and envelope equations with time-dependent frequency
The single-particle dynamics in a time-dependent focusing field is examined. The existence of the Courant-Snyder invariant, a fundamental concept in accelerator physics, is fundamentally a result of the corresponding symmetry admitted by the harmonic ...
Hong Qin, Ronald C. Davidson
doaj +1 more source
A boundary integral equation method in the frequency domain for cracks under transient loading [PDF]
Marina Menshykova +4 more
openalex +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Nonlinear Transformation of Differential Equations into Phase Space
Time-frequency representations transform a one-dimensional function into a two-dimensional function in the phase-space of time and frequency. The transformation to accomplish is a nonlinear transformation and there are an infinite number of such ...
Galleani Lorenzo, Cohen Leon
doaj +1 more source
This whitepaper introduces the MEI5 Time-Frequency Equation, a novel mathematical model for time distortion (Delta t) using modulation strength (mu), environmental resonance (r), and universal physical constants. Derived from Planck’s and Einstein’s principles, this equation enables measurable, repeatable synchronization behavior in systems with no ...
openaire +2 more sources

