Results 71 to 80 of about 2,177,340 (291)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Entrainment of frequency in evolution equations
Journal of Differential Equations, 1973 AbstractThe existence of periodic solutions near resonance is discussed using elementary methods for the evolution equation ·u = Au + ϵf(t, u) when the linear problem is totally degenerate (e2πA = I) and the period of f is entrained with ϵ (T = 2π(1 + ϵμ)).
Fink, James P., Hall, William S.
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On the Possibility of the Jerk Derivative in Electrical Circuits
Advances in Mathematical Physics, 2016 A subclass of dynamical systems with a time rate of change of acceleration are called Newtonian jerky dynamics. Some mechanical and acoustic systems can be interpreted as jerky dynamics. In this paper we show that the jerk dynamics are naturally obtained
J. F. Gómez-Aguilar +5 more
doaj +1 more source
Decoherence and purity of a driven solid-state qubit in Ohmic bath
, 2008 In this paper we study the decoherence and purity of a driven solid-state qubit in the Ohmic bath by using the method based on the master equation. At first, instead of solving the master equation we investigate the coefficients of the equation which ...
Chiorescu +27 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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The Excited of Electromagnetic Waves for Langmuir Waves in Relativistic Plasma
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2005 The study of the excited nonlinear Langmuir waves has been obtained in relativistic plasma in a resonance beat frequency for two high frequency laser waves.
A. S.Wahdain , J. A. Hassan
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Collective modes of a two-dimensional Fermi gas at finite temperature
, 2017 In this work we examine the breathing mode of a strongly interacting two-dimensional Fermi gas and the role of temperature on the anomalous breaking of scale invariance.
Hu, Hui +2 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
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