Results 131 to 140 of about 1,160,559 (367)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Modulation Algorithms for Manipulating Nuclear Spin States [PDF]

arXiv, 2013
We exploit the impact of exact frequency modulation on transition time of steering nuclear spin states from theoretical point of view. 1-stage and 2-stage Frequency-Amplitude-Phase modulation (FAPM) algorithms are proposed in contrast with 1-stage and 3-stage Amplitude-Phase modulation (APM) algorithms. The sufficient conditions are further present for
arxiv  

Loss of superfluidity in a Bose-Einstein condensate via forced resonant oscillations

, 2003
We predict the loss of superfluidity in a Bose-Einstein condensate in an axially symmetric harmonic trap alone during resonant collective oscillations via a classical dynamical transition.
Abdullaev, Adhikari, Adhikari, Adhikari, Adhikari, Adhikari, Adhikari, Adhikari, Anderson, Andrews, Burger, Cataliotti, Cataliotti, Courteille, Dalfovo, García-Ripoll, Greiner, Greiner, Inouye, Jin, Mewes, Morsch, Müller, Orzel, Pedri, Sadhan K. Adhikari, Smerzi, Stoof, Yukalov, Yukalov   +29 more
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Parametric Excitation of a Bose-Einstein Condensate: From Faraday Waves to Granulation

, 2019
We explore, both experimentally and theoretically, the response of an elongated Bose-Einstein condensate to modulated interactions. We identify two distinct regimes differing in modulation frequency and modulation strength. Longitudinal surface waves are
Bagnato, V. S., Hulet, R. G., Lode, A. U. J., Luo, D., Nguyen, J. H. V., Telles, G. D., Tsatsos, M. C.   +6 more
core   +2 more sources

Pitch Variations Arising from Certain Types of Frequency Modulation [PDF]

, 1937
Don Lewis, Milton Cowan, Grant Fairbanks
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Dynamic Distributed Brillouin Optical Fiber Sensing Based on Dual-Modulation by Combining Single Frequency Modulation and Frequency-Agility Modulation

IEEE Photonics Journal, 2017
Dynamic Brillouin optical fiber sensors based on fast scanning of Brillouin gain spectrum (BGS) are one of the most promising techniques to measure dynamic strains, where an ~11-GHz bandwidth arbitrary waveform generator (AWG) or a vector microwave ...
Dexin Ba, Dengwang Zhou, Benzhang Wang, Zhiwei Lu, Zhigang Fan, Yongkang Dong, Hui Li   +6 more
doaj   +1 more source

Frequency modulated laser beam with highly efficient intensity stabilisation [PDF]

Electronics Letters 41 (2005) 188-190, 2005
We analyse the limitation of the amplitude modulation rejection due to the spatial modulation of the output beam of an acousto-optic modulator used in an active laser beam stabilisation system when a frequency modulation of a few megahertz is applied to this modulator.
arxiv  

A Simple Method of Producing Wide-Band Frequency Modulation [PDF]

, 1949
H. Rakshit, Nantu Sarkar
openalex   +1 more source