Results 81 to 90 of about 2,755,944 (293)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation [PDF]

, 2012
In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study ...
Julianna Kobolak, Geißler, S., Mamo, S., Horsch, Marion, Horsch, M., Andras Dinnyes, Geissler, Sandra, Mamo, Solomon, Marion Horsch, Kobolak, J., Beckers, Johannes, Solomon Mamo, Kobolak, Julianna, Dinnyes, Andras, Beckers, J., Johannes Beckers, Sandra Geißler, Dinnyes, A.   +17 more
core   +1 more source

A Nonsurgical Embryo Transfer Technique for Fresh and Cultured Blastocysts in Rats

Journal of the American Association for Laboratory Animal Science, 2020
The use of a nonsurgical embryo transfer technique in rodents eliminates the potential pain, distress, and health complications that may result from a surgical procedure and as such, represents a refinement in rodent assisted reproductive techniques. A nonsurgical technique has not been previously developed for use with rat embryos.
Barbara J, Stone, Kendra H, Steele, Hongsheng, Men, Sarah J, Srodulski, Elizabeth C, Bryda, Angelika, Fath-Goodin   +5 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Table_1_Early Spontaneous Abortion in Fresh- and Frozen-Embryo Transfers: An Analysis of Over 35,000 Transfer Cycles.docx

, 2022
BackgroundThe aim of this study was to explore the risk factors for early spontaneous abortion (ESA) in fresh- and frozen-embryo transfers.MethodsThis retrospective cohort study comprised a total of 35,076 patients, including 15,557 women in the fresh ...
Wei-wei Liu (5654374), Guo-ning Huang (12960473), Wen-hong Chen (12960470), Qiao-li Chen (12960467), Hong Ye (460576), Jun Shuai (12960464)   +5 more
core   +1 more source

Prior copper intrauterine device use and reproductive outcomes after embryo transfer in IVF/ICSI cycles: a propensity score–matched cohort study

Frontiers in Cell and Developmental Biology
BackgroundThe copper intrauterine device (Cu-IUD) is a widely used long-term contraceptive method. However, whether prior Cu-IUD use, including long-term exposure, affects reproductive and neonatal outcomes after assisted reproductive technology (ART ...
Wenjie Huang, Wenjie Huang, Wenjie Huang, Liuyan Wei, Liuyan Wei, Liqiong Duan, Liqiong Duan, Huihui Xu, Jiaoyan Liu, Xiaoping Ren, Ni Tang, Ni Tang, Yanhuan Ou, Yanhuan Ou, Li Fan, Li Fan, Zhisong Chen, Huawei Wang   +17 more
doaj   +1 more source

Fresh embryos versus freeze-all embryos - transfer strategies: Nuances of a meta-analysis

JBRA Assisted Reproduction, 2017
The present meta-analysis aimed to evaluate whether the freeze-all strategy (Freeze/All-ET) could bring about improvements in the clinical assisted reproductive technique (ART) outcomes when compared with the fresh embryo transfer strategy (Fresh-ET) in patients undergoing an ART cycle in accordance with the mean number of oocytes collected.A ...
Dieamant, Felipe C, Petersen, Claudia G, Mauri, Ana L, Comar, V., Mattila, Mariana, Vagnini, Laura D, Renzi, Adriana, Petersen, Bruna, Nicoletti, Andreia, Oliveira, João Batista A, Baruffi, Ricardo LR, Franco Jr, Jose G   +11 more
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Embryo quality is the main factor affecting cumulative live birth rate after elective single embryo transfer in fresh stimulation cycles [PDF]

, 2015
Objective: The study was aimed to evaluate which factors affect the cumulative live birth rate after elective single embryo transfer in women younger than 36 years.
Martikainen, Hannu, Niinimaki, Maarit, Veleva, Zdravka   +2 more
core   +1 more source

Fresh or frozen day 6 blastocyst transfer: is there still a question?

Reproductive Biology and Endocrinology
Background The Live Birth Rate (LBR) after day 5 (D5) blastocyst transfer is significantly higher than that with D6 embryos in both fresh and frozen-vitrified embryo transfer cycles, according to the most recently published meta-analyses.
Lucile Ferreux, Mathilde Bourdon, Ahmed Chargui, Julie Firmin, Chloé Maignien, Pietro Santulli, Catherine Patrat, Khaled Pocate-Cheriet   +7 more
doaj   +1 more source