Results 191 to 200 of about 1,671,645 (312)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Detection of Murine Norovirus on Fresh Produce Through a CRISPR/Cas13a RNase-Based Capsid Integrity Assay. [PDF]

Food Environ Virol
Ossio A, Merino-Mascorro A, Leon JS, Heredia N, Garcia S.   +4 more
europepmc   +1 more source

Fresh Produce as a Potential Vector and Reservoir for Human Bacterial Pathogens: Revealing the Ambiguity of Interaction and Transmission. [PDF]

Microorganisms, 2023
Esmael A, Al-Hindi RR, Albiheyri RS, Alharbi MG, Filimban AAR, Alseghayer MS, Almaneea AM, Alhadlaq MA, Ayubu J, Teklemariam AD.   +9 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Emerging and Innovative Technologies for the Sanitization of Fresh Produce: Advances, Mechanisms, and Applications for Enhancing Food Safety and Quality. [PDF]

Foods
Jin Y, Adhikari A.
europepmc   +1 more source

Effect of Food Matrix and Treatment Time on the Effectiveness of Grape Seed Extract as an Antilisterial Treatment in Fresh Produce. [PDF]

Microorganisms, 2023
Ghorbani Tajani A, Bisha B.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Engineering PVA-CNF-MOF Composite Films for Active Packaging: Enhancing Mechanical Strength, Barrier Performance, and Stability for Fresh Produce Preservation. [PDF]

Molecules
Carrasco S, Amaro-Gahete J, Espinosa E, Benítez A, Romero-Salguero FJ, Rodríguez A.   +5 more
europepmc   +1 more source

Identification and Characterization of Antibiotic-Resistant, Gram-Negative Bacteria Isolated from Korean Fresh Produce and Agricultural Environment. [PDF]

Microorganisms, 2023
Jeong S, Kim I, Kim BE, Jeong MI, Oh KK, Cho GS, Franz CMAP.   +6 more
europepmc   +1 more source

Fresh Produce Loyalty Card [PDF]

, 2014

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