Results 1 to 10 of about 187,266 (192)

Repurposing existing drugs: identification of SARS-CoV-2 3C-like protease inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19). Since its emergence, the COVID-19 pandemic has not only distressed medical services but also caused economic upheavals, marking urgent ...
Wei-Chung Chiou   +6 more
doaj   +1 more source

FRET-based carbazole-fluorescein ionic nanoparticle for use as an effective bioimaging agent [PDF]

open access: yesBiofunctional Materials, 2023
Fӧrster resonance energy transfer (FRET)-based systems are widely applicable in many areas of interest. In this study, a novel FRET-based ionic material (IM) was synthesized by pairing carbazole imidazolium cation (CI+) with fluorescein anion (Fl2 ...
Amanda Jalihal   +7 more
doaj   +1 more source

KONTRABASIN GELİŞİM SÜRECİNDEKİ DEĞİŞİMLERİN İCRA STANDARTLARINA ETKİLERİ

open access: yesTrakya University Journal of Social Sciences, 2023
18. Yüzyılda kontrabas, orkestradaki ritmik ve armonik yapıyı oluşturmakta temel olarak kullanılmıştır. Kontrabasın kalın sesi armoninin temel notalarını oluştururken ritmik unsurları da ifade etmekte başarılı olmuştur.
Sela Can DÖKMECİ, Türkmen Ozan TANIŞ
doaj   +1 more source

Role of an Aromatic–Aromatic Interaction in the Assembly and Trafficking of the Zebrafish Panx1a Membrane Channel

open access: yesBiomolecules, 2020
Pannexin 1 (Panx1) is a ubiquitously expressed hexameric integral membrane protein known to function as an adenosine triphosphate (ATP) release channel. Panx1 proteins exist in unglycosylated core form (Gly0).
Ksenia Timonina   +2 more
doaj   +1 more source

Quantitative FRET-FLIM-BlaM to Assess the Extent of HIV-1 Fusion in Live Cells

open access: yesViruses, 2020
The first steps of human immunodeficiency virus (HIV) infection go through the engagement of HIV envelope (Env) with CD4 and coreceptors (CXCR4 or CCR5) to mediate viral membrane fusion between the virus and the host.
Irene Carlon-Andres, Sergi Padilla-Parra
doaj   +1 more source

FRET or No FRET: A Quantitative Comparison [PDF]

open access: yesBiophysical Journal, 2003
Fluorescence resonance energy transfer (FRET) is a technique used to measure the interaction between two molecules labeled with two different fluorophores (the donor and the acceptor) by the transfer of energy from the excited donor to the acceptor.
Berney, Claude, Danuser, Gaudenz
openaire   +2 more sources

Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging microscopy (FLIM) data. [PDF]

open access: yes, 2020
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local DNA template access, and through continuous dynamic rearrangements, regulates genome function [1].
Gratton, Enrico   +4 more
core   +3 more sources

Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Coronavirus disease 2019 (COVID-19) has been a pandemic disease of which the termination is not yet predictable. Currently, researches to develop vaccines and treatments is going on globally to cope with this disastrous disease.
Seri Jo   +4 more
doaj   +1 more source

Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor

open access: yesJournal of Biomechanical Science and Engineering, 2016
Tension in actin filaments plays crucial roles in multiple cellular functions, although little is known about tension dynamics of cells during adhesion to substrates.
Junfeng WANG   +7 more
doaj   +1 more source

Nanoscale control of single molecule Förster resonance energy transfer by a scanning photonic nanoantenna

open access: yesNanophotonics, 2020
Förster Resonance Energy Transfer (FRET) is a widely applied technique in biology to accurately measure intra- and inter-molecular interactions at the nanometre scale.
Sanz-Paz Maria   +4 more
doaj   +1 more source

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