Results 81 to 90 of about 44,208 (254)
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
A New Way for Effective Reducing Brake Temperature and Noise of Brake Pad
机车电传动, 2015 With the theoretical analysis of friction brake temperature and brake noise, and adjusting formulation and process, a new type of microporous composite brake pad was developed successfully, which had a microporous structure to effectively reduce friction
JIN Jiansheng +4 more
doaj
The commercialization of labour markets: Evidence from wage inequality in the Middle Ages
The Economic History Review, EarlyView.Abstract This paper moves beyond the focus on ‘average’ wage trends in pre‐industrial economies by examining the broad diversity of pay rates and forms of remuneration across occupations and regions in medieval England. We find that whilst some workers enjoyed substantial growth in wage rates after the Black Death, there was a large group who ...
Jordan Claridge +2 more
wiley +1 more source
Evaluation of materials and design modifications for aircraft brakes [PDF]
A test program is described which was carried out to evaluate several proposed design modifications and several high-temperature friction materials for use in aircraft disk brakes.
Ho, T. L. +2 more
core +1 more source
Estimation of the normal contact stiffness for frictional interface in sticking and sliding conditions [PDF]
, 2019 Modeling of frictional contact systems with high accuracy needs the knowledge of several contact parameters, which are mainly related to the local phenomena at the contact interfaces and affect the complex dynamics of mechanical systems in a prominent ...
Baillet, L. +4 more
core +1 more source
The Narrative Continent: Discursive Recognition and the EU's Technological Actorness
JCMS: Journal of Common Market Studies, EarlyView.Abstract Recognition in global politics is not only earned through institutions or capabilities; it is narrated into being. This article investigates how the European Union (EU) is framed as a technological actor in global discourse, focusing on the symbolic dynamics of discursive recognition.
Mahmoud Javadi
wiley +1 more source
Темпи нагрівання та охолодження ободів металевих фрикційних елементів гальмівних пристроїв [PDF]
, 2011 Для оцінки темпів нагрівання і охолодження ободів металевих фрикційних елементів гальмівних пристроїв використано метод регулярного режиму. Проілюстровано особливості визначення теплових характеристик металевих фрикційних елементів гальмівних пристроїв ...
Бекіш, І. О. +3 more
core
Representing, Re‐presenting, or Producing the Past? Memory Work amongst Museum Employees
Journal of Management Studies, EarlyView.Abstract Though it is widely understood that the past can be an important resource for organizations, less is known about the micro‐level skills and choices that help to materialize different representations of the past. We understand these micro‐level skills and choices as a practice: ‘memory work’ – a banner term gathering various activities that ...
Jeremy Aroles +3 more
wiley +1 more source
Expert supervision of an anti-skid control system of a commercial aircraft [PDF]
, 1996 A rule-based supervising system that incorporates fuzzy logic has been designed to back-up a conventional anti-skid braking system (ABS). Expressing the expert knowledge about the ABS in terms of linguistic rules, the supervising fuzzy system adapts the ...
Bordeneuve-Guibé, Joël +3 more
core
Journal of Management Studies, EarlyView.Abstract Hubs and participants of mature ecosystems increasingly compete with de alio entrants that are hubs of more innovative ecosystems. Prior research shows how these asymmetric de alio entrants frame to win over participants from mature ecosystems and suggests that hubs of these ecosystems should respond by encouraging innovation among ...
Georg Reischauer +2 more
wiley +1 more source