BMC Evolutionary Biology, 2019 Background Frizzled family members belong to G-protein coupled receptors and encode proteins accountable for cell signal transduction, cell proliferation and cell death. Members of Frizzled receptor family are considered to have critical roles in causing
Suman Seemab +5 more
doaj +1 more source
WNT5a export onto extracellular vesicles studied at single‐molecule and single‐vesicle resolution
The FEBS Journal, EarlyView.WNT signaling, which orchestrates tissue development and homeostasis, is mediated by hydrophobic WNT proteins traveling from secreting to receiving cells on various carriers. Here, fusion constructs of fluorescent proteins with WNT5a were developed and functionally validated.
Antonia Schubert +16 more
wiley +1 more source
Remote activation of the Wnt/β-catenin signalling pathway using functionalised magnetic particles.
PLoS ONE, 2015 Wnt signalling pathways play crucial roles in developmental biology, stem cell fate and tissue patterning and have become an attractive therapeutic target in the fields of tissue engineering and regenerative medicine.
Michael Rotherham, Alicia J El Haj
doaj +1 more source
A novel deletion in KRT75L4 and KRT75 mediating the frizzle trait in an Indonesian frizzle chicken [PDF]
AIP Conference Proceedings, 2021 Sayli Salsabila +9 more
openaire +2 more sources
Interaction of Frizzled Related Protein (FRP) with Wnt Ligands and the Frizzled Receptor Suggests Alternative Mechanisms for FRP Inhibition of Wnt Signaling [PDF]
, 1999 Anna Bafico +5 more
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Periodontology 2000, EarlyView.Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein. [PDF]
, 1996 Hitoshi Sawa +2 more
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Inflammation and mechanical force‐induced bone remodeling
Periodontology 2000, EarlyView.Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
Insulin resistance is associated with Sfrp5 in obstructive sleep apnea
Brazilian Journal of Otorhinolaryngology, 2019 Introduction: Obstructive sleep apnea, a common disease, is usually complicated by insulin resistance and type 2 diabetes mellitus. Adipokine is considered to play an important role in the development of insulin resistance and type 2 diabetes mellitus in
Shibo Sun +5 more
doaj
The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases [PDF]
, 1998 Yu Katherine Xu, Roel Nusse
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