Results 131 to 140 of about 53,326 (285)
Insights into the mechanism of inhibition of bone morphogenetic protein-1 (BMP-1) by the secreted frizzled related protein Sizzled [PDF]
, 2022 Urvashi Sharma +9 more
openalex +1 more source
, 2017 The polarisation of cells and tissues is fundamental for tissue morphogenesis during biological development and regeneration. A deeper understanding of biological polarity pattern formation can be gained from the consideration of pattern reorganisation ...
Brusch, Lutz +3 more
core +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen +5 more
wiley +1 more source
Estudo da regulação transcricional do COL18A1 e análise funcional do domínio Frizzled [PDF]
, 2009 Érika Kague
openalex +1 more source
Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors
Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings +6 more
wiley +1 more source
Disruption of the Non-Canonical WNT Pathway in Lung Squamous Cell Carcinoma
Clinical Medicine Insights: Oncology, 2008 Disruptions of beta-catenin and the canonical Wnt pathway are well documented in cancer. However, little is known of the non-canonical branch of the Wnt pathway.
Eric H.L. Lee +9 more
doaj +1 more source