Serum adiponectin level is negatively related to insulin resistance in women with polycystic ovary syndrome. [PDF]
Yang J+7 more
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Assessment of the Role of miR-30a-5p on the Proliferation and Apoptosis of Hair Follicle Stem Cells. [PDF]
Wang Y+7 more
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Wnt signaling in cancer: from biomarkers to targeted therapies and clinical translation. [PDF]
Tufail M, Jiang CH, Li N.
europepmc +1 more source
frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma.
Monfries C+11 more
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Case Report: Phosphaturic mesenchymal tumor presenting solely as knee pain without hypophosphatemia. [PDF]
Cao Q, Cheng C, Dai Z.
europepmc +1 more source
Advances in intestinal flora for the development, diagnosis and treatment of CRC. [PDF]
Hu R+8 more
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Molecular Cloning of Frizzled-10, a Novel Member of the Frizzled Gene Family
Biochemical and Biophysical Research Communications, 1999The Frizzled genes encode WNT receptors. Frizzled-10 (FZD10), a novel member of the Frizzled gene family, has been cloned and characterized. Nucleotide sequence analysis showed that human FZD10 gene encodes a seven-transmembrane-receptor of 581 amino acids, with the N-terminal cysteine-rich domain and the C-terminal Ser/Thr-Xxx-Val motif.
Masaru Katoh+5 more
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Structure-function analysis of Frizzleds
Cellular Signalling, 2006Frizzleds, cell surface receptors that mediate the actions of Wnt ligands on early development, are heptahelical (based upon hydropathy analysis) and couple to heterotrimeric G proteins. The primary structure of all ten mammalian Frizzleds display many landmarks observed in virtually all G protein-coupled receptors, including an exofacial N-terminus ...
Hsien-yu Wang, Craig C. Malbon, Tong Liu
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Upregulation of frizzled 9 in astrocytomas
Neuropathology and Applied Neurobiology, 2006Wnt/frizzled (FZD) cascades play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. The potential involvement of this pathway in tumorigenesis has been established in several types of cancers.
K. Guo+6 more
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Wnt/Frizzled signaling in angiogenesis
Angiogenesis, 2008The roles of growth factors such as angiopoietin (Ang) and vascular endothelial growth factor (VEGF) in angiogenesis have been known for some time, yet we have just an incipient appreciation for the contribution of Wnts to this process. Cellular proliferation and polarity, apoptosis, branching morphogenesis, inductive processes, and the maintenance of ...
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