Results 21 to 30 of about 53,326 (285)

Frizzled Domain [PDF]

, 2020
National Cancer Institute
openaire   +2 more sources

Norrin and Frizzled [PDF]

Developmental Cell, 2004
Christof Niehrs
openaire   +2 more sources

Clinical significance of frizzled homolog 3 protein in colorectal cancer patients. [PDF]

PLoS ONE, 2013
Frizzled homolog 3 receptor was up-regulated in several gastrointestinal cancers such as esophageal and gastric cancers. Moreover, frizzled homolog 3 has recently reported to be expressed in colorectal adenoma specimens.
Sze Chuen Cesar Wong, Catherine Wan He, Charles Ming Lok Chan, Amanda Kit Ching Chan, Heong Ting Wong, Moon Tong Cheung, Lewis Lai Yin Luk, Thomas Chi Chuen Au, Man Kin Chiu, Brigette Buig Yue Ma, Anthony Tak Cheung Chan   +10 more
doaj   +1 more source

Wnt-Frizzled Signaling Regulates Activity-Mediated Synapse Formation

Frontiers in Molecular Neuroscience, 2021
The formation of synapses is a tightly regulated process that requires the coordinated assembly of the presynaptic and postsynaptic sides. Defects in synaptogenesis during development or in the adult can lead to neurodevelopmental disorders, neurological
Samuel Teo, Patricia C. Salinas
doaj   +1 more source

Activation of Frizzled-7 attenuates blood–brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice

Fluids and Barriers of the CNS, 2021
Background Destruction of blood–brain barrier (BBB) ​​is one of the main mechanisms of secondary brain injury following intracerebral hemorrhage (ICH).
Wei He, Qin Lu, Prativa Sherchan, Lei Huang, Xin Hu, John H. Zhang, Haibin Dai, Jiping Tang   +7 more
doaj   +1 more source

Wnt Signaling: Pathogen Incursion and Immune Defense

Frontiers in Immunology, 2019
Wnt ligands interact with the transmembrane cell surface receptors Frizzled and ROR/RYK to initiate complex signaling cascades that are crucial for cell physiology and the proper functioning of the immune system.
Suborno Jati, Tresa Rani Sarraf, Debdut Naskar, Malini Sen   +3 more
doaj   +1 more source

Growth patterns and heat tolerance analysis of dwarf chicken with frizzled feather. [PDF]

Poult Sci
Li G, Xie T, Zhu Z, Bin C, Ali S, Guo D, Wang X, Li L, Huang X, Zhang B, Zhang L.   +10 more
europepmc   +2 more sources

Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. [PDF]

, 2015
Frizzled is the earliest discovered glycosylated Wnt protein receptor and is critical for the initiation of Wnt signaling. Antagonizing Frizzled is effective in inhibiting the growth of multiple tumor types.
Baday, Yiressy C, Bao, Ju, Guibao, Cristina, Lee, Ho-Jin, Li, Lin, Miller, Ami, Wu, Dianqing, Wu, Jibo, Zhang, Chi, Zheng, Jie J   +9 more
core   +2 more sources

The Emerging Mechanisms of Wnt Secretion and Signaling in Development

Frontiers in Cell and Developmental Biology, 2021
Wnts are highly-conserved lipid-modified secreted proteins that activate multiple signaling pathways. These pathways regulate crucial processes during various stages of development and maintain tissue homeostasis in adults.
Shefali Mehta, Swapnil Hingole, Varun Chaudhary   +2 more
doaj   +1 more source

Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans

eLife, 2019
During development, the nervous system undergoes a refinement process by which neurons initially extend an excess number of neurites, the majority of which will be eliminated by the mechanism called neurite pruning.
Menghao Lu, Kota Mizumoto
doaj   +1 more source