Results 41 to 50 of about 51,161 (270)

A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin [PDF]

, 2017
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original ...
A Muller, A Schlesinger, AK Classen, B Chini, B Goldstein, B Lu, B Steensel Van, C Luxenburg, CB O’Connell, CJ Formstone, CR Vinson, D Devenport, D Devenport, D Shi, DR Tree, F Bosveld, F Pietro Di, FD Park, H Chang, H Strutt, J Cabello, J Chae, J Hamann, J Taylor, JA Curtin, JD Axelrod, K Doyle, LL Yates, M Gho, M Segalen, M Thery, MS Lu, N Guo, O Hertwig, R Shrestha, S Bolte, S Saburi, T Langenhan, T Lechler, T Usui, T Walston, WT Gibson, X Zhang, Y Bei, Y Gong, Y Mao, Y Qu, Y Wang   +47 more
core   +3 more sources

Structural Basis of Wnt Recognition by Frizzled [PDF]

Science, 2012
Dissecting Wnt/Fz Interaction Wnt proteins activate the transmembrane receptor Frizzled (Fz) to initiate pathways central to vertebrate and invertebrate development. Wnts are palmitoylated, which has complicated structural and functional characterization. Janda et al.
Christoph Thomas, K. Christopher Garcia, Claudia Y. Janda, Deepa Waghray, Aron M. Levin   +4 more
openaire   +2 more sources

Signaling of human frizzled receptors to the mating pathway in yeast. [PDF]

PLoS ONE, 2007
Frizzled receptors have seven membrane-spanning helices and are considered as atypical G protein-coupled receptors (GPCRs). The mating response of the yeast Saccharomyces cerevisiae is mediated by a GPCR signaling system and this model organism has been ...
Dietmar Dirnberger, Klaus Seuwen
doaj   +1 more source

Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling [PDF]

, 2015
Peer reviewedPublisher ...
Abal, Miguel, Aznar, Nicolas, Barbazán, Jorge, Dunkel, Ying, Garcia-Marcos, Mikel, Ghosh, Pradipta, Goel, Ajay, Janssen, Klaus-Peter, Lopez-Sanchez, Inmaculada, Marivin, Arthur, Midde, Krishna K, Murray, Fiona, Nitsche, Ulrich, Pavlova, Yelena, Willert, Karl   +14 more
core   +5 more sources

The wnt-frizzled cascade in cardiovascular disease [PDF]

Cardiovascular Research, 2002
Time for primary review 31 days. Wnt-proteins constitute a family of secreted cystein-rich glycosylated proteins, involved in a variety of modeling and remodeling processes including cell proliferation, differentiation, apoptosis and the control of cell orientation [1–3].
Jos F.M. Smits, Mat J.A.P. Daemen, Marielle E. van Gijn, W. Matthijs Blankesteijn   +3 more
openaire   +3 more sources

Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance [PDF]

, 2016
Background A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in order to assemble neural circuits that control behavior.
Purdy, Ashley M., Sun, Simon D., Walsh, Gregory S.   +2 more
core   +2 more sources

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

eLife, 2019
Secreted Wnt proteins regulate development and adult tissue homeostasis by binding and activating cell-surface Frizzled receptors and co-receptors including LRP5/6.
Yuyong Tao, Monika Mis, Levi Blazer, Mart Ustav Jnr, Zachary Steinhart, Rony Chidiac, Elli Kubarakos, Siobhan O'Brien, Xiaomei Wang, Nick Jarvik, Nish Patel, Jarrett Adams, Jason Moffat, Stephane Angers, Sachdev S Sidhu   +14 more
doaj   +1 more source

A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings

G3: Genes, Genomes, Genetics, 2016
Most mutant alleles in the Fz-PCP pathway genes were discovered in classic Drosophila screens looking for recessive loss-of-function (LOF) mutations. Nonetheless, although Fz-PCP signaling is sensitive to increased doses of PCP gene products, not many ...
Jose Maria Carvajal-Gonzalez, Sonia Mulero-Navarro, Michael Smith, Marek Mlodzik   +3 more
doaj   +1 more source

Effects of dietary chitosan oligosaccharides supplementation on meat quality, chemical composition and anti-oxidant capacity in frizzled chickens

Italian Journal of Animal Science, 2023
The aim of this study was to evaluate dietary chitosan oligosaccharides (COS) supplementation on meat quality, chemical composition and oxidative stability in frizzled chickens.
Ruixia Lan, Xiaochun Chen, Yuhua Zhang, Huiwen Luo   +3 more
doaj   +1 more source

Dissecting the impact of Frizzled receptors in Wnt/beta-catenin signaling of human mesenchymal stem cells [PDF]

, 2012
Wnt/beta-catenin signaling is of fundamental importance in the regulation of self-renewal, migration/invasion, and differentiation of human mesenchymal stem cells (hMSCs).
Capovilla, Simon, Fernsebner, Katharina, Geissler, Claudia, Jochum, Marianne, Kolben, Thomas, Lechner, Felix, Neth, Peter, Peroebner, Iris, Ruiz-Heinrich, Lourdes   +8 more
core   +2 more sources