Results 41 to 50 of about 53,326 (285)
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis
eLife, 2020 Wnt signaling through the Frizzled (FZD) family of serpentine receptors is essential for embryogenesis and homeostasis, and stringent control of the FZD protein level is critical for stem cell regulation.
Maorong Chen +6 more
doaj +1 more source
The distribution of Dishevelled in convergently extending mesoderm [PDF]
, 2013 Convergent extension (CE) is a conserved morphogenetic movement that drives axial lengthening of the primary body axis and depends on the planar cell polarity (PCP) pathway.
Bretschneider, Till +3 more
core +1 more source
Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children
Cells, 2019 Identification and isolation of neural progenitor cells from the human enteric nervous system (ENS) is currently hampered by the lack of reliable, specific markers.
Peter H. Neckel +8 more
doaj +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Wnt-3a Induces Cytokine Release in Human Mast Cells
Cells, 2019 Mast cells are well known for their detrimental effects in allergies and asthma, and Wnt signaling has recently been implicated in asthma and other airway diseases. However, it is not known if or how Wnts affect human mast cells.
Julia Tebroke +5 more
doaj +1 more source
Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats. [PDF]
PLoS ONE, 2012 BackgroundWnt proteins are a large family of molecules that are critically involved in multiple central nervous system (CNS) developmental processes.
Pau Gonzalez +4 more
doaj +1 more source
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]
, 2020 Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles +3 more
core +1 more source
Signaling of human frizzled receptors to the mating pathway in yeast. [PDF]
PLoS ONE, 2007 Frizzled receptors have seven membrane-spanning helices and are considered as atypical G protein-coupled receptors (GPCRs). The mating response of the yeast Saccharomyces cerevisiae is mediated by a GPCR signaling system and this model organism has been ...
Dietmar Dirnberger, Klaus Seuwen
doaj +1 more source
Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt Signalling. [PDF]
, 2016 Research over the last decade recognized the importance of novel molecular pathways in pathogenesis of intracranial meningiomas. In this review, we focus on human brain tumours meningiomas and the involvement of Wnt signalling pathway genes and proteins ...
Kafka, Anja +2 more
core +2 more sources
G3: Genes, Genomes, Genetics, 2016 Most mutant alleles in the Fz-PCP pathway genes were discovered in classic Drosophila screens looking for recessive loss-of-function (LOF) mutations. Nonetheless, although Fz-PCP signaling is sensitive to increased doses of PCP gene products, not many ...
Jose Maria Carvajal-Gonzalez +3 more
doaj +1 more source