Results 81 to 90 of about 56,649 (315)
Advanced Materials, EarlyView.This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang +3 more
wiley +1 more source
The polarity protein VANG-1 antagonizes Wnt signaling by facilitating Frizzled endocytosis [PDF]
, 2018 Signaling that instructs the migration of neurons needs to be tightly regulated to ensure precise positioning of neurons and subsequent wiring of the neuronal circuits.
Chen, Chun-Hao +5 more
core +1 more source
Cell Proliferation, 2019 Mesenchymal stem cell (MSC)‐based dental tissue regeneration is a potential treatment method in future, while inflammation and hypoxia niche will affect MSC‐mediated tissue regeneration.
Haoqing Yang +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang +10 more
wiley +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Cell Communication and Signaling, 2005 Background Secreted Frizzled related proteins (SFRPs) are extracellular regulators of Wnt signaling. These proteins contain an N-terminal cysteine rich domain (CRD) highly similar to the CRDs of the Frizzled family of seven-transmembrane proteins that ...
Medina Araceli +3 more
doaj +1 more source
Wnt Binding Affinity Prediction for Putative Frizzled-Type Cysteine-Rich Domains
International Journal of Molecular Sciences, 2019 Several proteins other than the frizzled receptors (Fzd) and the secreted Frizzled-related proteins (sFRP) contain Fzd-type cysteine-rich domains (CRD).
Mark Agostino, S. Pohl
semanticscholar +1 more source
Frizzled-7 is required for Xenopus heart development [PDF]
Biology Open, 2017 Wnt signalling regulates cardiogenesis during specification of heart tissue and the morphogenetic movements necessary to form the linear heart. Wnt11 mediated non-canonical signalling promotes early cardiac development whilst Wnt11-R, which is expressed later, also signals through the non-canonical pathway to promote heart development.
Joanna Mulvaney +3 more
openaire +6 more sources
ChemMedChem, EarlyView.ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone +17 more
wiley +1 more source
A Non-canonical Wnt Signature Correlates With Lower Survival in Gastric Cancer
Frontiers in Cell and Developmental Biology, 2021 Genetic evidence suggests a role for the Wnt/β-catenin pathway in gastric cancer. However, Wnt5a, regarded as a prototypical non-canonical Wnt ligand, has also been extensively associated with this disease.
Pablo Astudillo
doaj +1 more source