Non-Lethal Detection of Frog Virus 3-Like (RUK13) and Common Midwife Toad Virus-Like (PDE18) Ranaviruses in Two UK-Native Amphibian Species [PDF]
Ranaviruses have been involved in amphibian mass mortality events worldwide. Effective screening to control this pathogen is essential; however, current sampling methods are unsuitable for the detection of subclinical infections.
Charlotte E. Ford +7 more
doaj +2 more sources
Inflammation-induced reactivation of the ranavirus Frog Virus 3 in asymptomatic Xenopus laevis. [PDF]
Natural infections of ectothermic vertebrates by ranaviruses (RV, family Iridoviridae) are rapidly increasing, with an alarming expansion of RV tropism and resulting die-offs of numerous animal populations.
Jacques Robert +4 more
doaj +2 more sources
Class A Scavenger Receptors Are Used by Frog Virus 3 During Its Cellular Entry [PDF]
Frog virus 3 (FV3) is the type species of the genus Ranavirus (family Iridoviridae). FV3 and FV3-like viruses are globally distributed infectious agents with the capacity to replicate in three vertebrate classes (teleosts, amphibians, and reptiles).
Nguyen T. K. Vo +4 more
doaj +2 more sources
Isolation and Characterization of a Frog Virus 3 Strain from a Wood Frog (Rana sylvatica) in Wood Buffalo National Park [PDF]
Members of the Iridoviridae family, genus Ranavirus, represent a group of globally emerging pathogens of ecological and economic importance. In 2017, an amphibian die-off of wood frogs (Rana sylvatica) and boreal chorus frogs (Pseudacris maculata) was ...
Samantha R. Logan +5 more
doaj +2 more sources
Cytokinins Reduce Viral Replication and Alter Plaque Morphology of Frog Virus 3 In Vitro [PDF]
Cytokinins (CKs) are a group of N6-substituted signaling molecules whose biosynthesis and metabolism have been documented in all kingdoms of life, including vertebrates.
Mark Seegobin +3 more
doaj +2 more sources
First Report of Endemic Frog Virus 3 (FV3)-like Ranaviruses in the Korean Clawed Salamander (Onychodactylus koreanus) in Asia [PDF]
Frog virus 3 (FV3) in the genus Ranavirus of the family Iridoviridae causes mass mortality in both anurans and urodeles worldwide; however, the phylogenetic origin of FV3-like ranaviruses is not well established.
Jongsun Kim +4 more
doaj +2 more sources
Detection of Frog Virus 3 by Integrating RPA-CRISPR/Cas12a-SPM with Deep Learning [PDF]
Zhengyang Lei +19 more
doaj +2 more sources
Case report: ranavirus infections in captive eastern box turtles (Terrapene carolina carolina) in Japan [PDF]
Ranaviruses are broad host-range pathogens that cause fatal infections in ectothermic vertebrates, including fish, amphibians, and reptiles and are considered emerging infectious diseases. This report describes a case of ranavirus infection identified at
Kenichi Tamukai +4 more
doaj +2 more sources
Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection [PDF]
Besides the central role of classical Major Histocompatibility Complex (MHC) class Ia-restricted conventional Cluster of Differentiation 8 (CD8) T cells in antiviral host immune response, the amphibian Xenopus laevis critically rely on MHC class I-like ...
Eva-Stina Isabella Edholm +4 more
doaj +2 more sources
A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene [PDF]
Background Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses.
Montgomery Roy D +3 more
doaj +2 more sources

